Analysis of apoptosis on chip: Why the move to chip technology?

F. Wolbers, Helene Andersson, Albert van den Berg, Clemens Haanen, I. Vermes

    Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

    Abstract

    Apoptosis refers to a specific form of programmed cell death, which guarantees the welfare of the whole organism through the elimination of unwanted cells. The duration of apoptosis is short, involves single cells with morphological changes only after the point of no return, ending with phagocytosis without reaction in the neighbour cell. A number of techniques exist to measure cell death, but we still looking for a simple, specific and sensitive technique which offers the possibility to measure apoptosis on single cell level, without staining, in real time, with high-throughput. The Lab-in-a-Cell concept by using chip technology offers such a tool.
    Original languageUndefined
    Title of host publicationLab-on-Chips for Cellomics
    Subtitle of host publicationMicro and Nanotechnologies for Life Sciences
    EditorsHelene Andersson, Albert van den Berg
    Place of PublicationDordrecht
    PublisherKluwer Academic Publishers
    Pages197-224
    Number of pages360
    ISBN (Electronic)978-1-4020-2975-2
    ISBN (Print)1-4020-2860-1
    DOIs
    Publication statusPublished - 2004

    Keywords

    • METIS-218854
    • IR-47878

    Cite this

    Wolbers, F., Andersson, H., van den Berg, A., Haanen, C., & Vermes, I. (2004). Analysis of apoptosis on chip: Why the move to chip technology? In H. Andersson, & A. van den Berg (Eds.), Lab-on-Chips for Cellomics: Micro and Nanotechnologies for Life Sciences (pp. 197-224). Dordrecht: Kluwer Academic Publishers. https://doi.org/10.1007/978-1-4020-2975-2_8