Apoptosis refers to a specific form of programmed cell death, which guarantees the welfare of the whole organism through the elimination of unwanted cells. The duration of apoptosis is short, involves single cells with morphological changes only after the point of no return, ending with phagocytosis without reaction in the neighbour cell. A number of techniques exist to measure cell death, but we still looking for a simple, specific and sensitive technique which offers the possibility to measure apoptosis on single cell level, without staining, in real time, with high-throughput. The Lab-in-a-Cell concept by using chip technology offers such a tool.
|Title of host publication||Lab-on-Chips for Cellomics|
|Subtitle of host publication||Micro and Nanotechnologies for Life Sciences|
|Editors||Helene Andersson, Albert van den Berg|
|Place of Publication||Dordrecht|
|Publisher||Kluwer Academic Publishers|
|Number of pages||360|
|Publication status||Published - 2004|