Antithrombin activity of a polyelectrolyte synthesized from cis-1,4-polyisoprene

T. Beugeling, L. van der Does, A. Bantjes, W.L. Sederel

Research output: Contribution to journalArticleAcademic

19 Citations (Scopus)
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A polyelectrolyte synthesized from cis-1,4-polyisoprene, containing aminosulfonate and carboxylate groups was shown to have an anticoagulant activity of about 1/30 compared with heparin. Because the substance prevents the coagulation of plasma in the presence of thrombin it is assumed that it acts as an antithrombin.
Original languageEnglish
Pages (from-to)375-379
JournalJournal of biomedical materials research
Issue number6
Publication statusPublished - 1974


  • IR-70742


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