Apoptosis chip for drug screening

F. Wolbers

    Research output: ThesisPhD Thesis - Research UT, graduation UT

    29 Downloads (Pure)

    Abstract

    This thesis describes the process of the development towards a microfluidic platform to perform apoptosis studies on chip in real-time at a single-cell level. The requirements for such cell-based assays are discussed as well as the advantages of using microfluidics for cellular analysis. Our main interest is focused on breast cancer cells. Ultimately, this microfluidic chip has to function as a new analytical device for the clinic to provide patients with the best individual therapy.
    Original languageUndefined
    Awarding Institution
    • University of Twente
    Supervisors/Advisors
    • van den Berg, Albert , Supervisor
    • Vermes, I., Supervisor
    • Andersson, Helene, Supervisor
    Thesis sponsors
    Award date8 Jun 2007
    Place of PublicationZutphen
    Publisher
    Print ISBNs978-90-365-2499-5
    Publication statusPublished - 8 Jun 2007

    Keywords

    • METIS-241707
    • EWI-10321
    • IR-57881

    Cite this

    Wolbers, F. (2007). Apoptosis chip for drug screening. Zutphen: University of Twente.
    Wolbers, F.. / Apoptosis chip for drug screening. Zutphen : University of Twente, 2007. 214 p.
    @phdthesis{469180a5873740c18822badbfbab63fc,
    title = "Apoptosis chip for drug screening",
    abstract = "This thesis describes the process of the development towards a microfluidic platform to perform apoptosis studies on chip in real-time at a single-cell level. The requirements for such cell-based assays are discussed as well as the advantages of using microfluidics for cellular analysis. Our main interest is focused on breast cancer cells. Ultimately, this microfluidic chip has to function as a new analytical device for the clinic to provide patients with the best individual therapy.",
    keywords = "METIS-241707, EWI-10321, IR-57881",
    author = "F. Wolbers",
    note = "The research described in this thesis was supported by Medisch Spectrum Twente, Hospital Group, Enschede, The Netherlands",
    year = "2007",
    month = "6",
    day = "8",
    language = "Undefined",
    isbn = "978-90-365-2499-5",
    publisher = "University of Twente",
    address = "Netherlands",
    school = "University of Twente",

    }

    Wolbers, F 2007, 'Apoptosis chip for drug screening', University of Twente, Zutphen.

    Apoptosis chip for drug screening. / Wolbers, F.

    Zutphen : University of Twente, 2007. 214 p.

    Research output: ThesisPhD Thesis - Research UT, graduation UT

    TY - THES

    T1 - Apoptosis chip for drug screening

    AU - Wolbers, F.

    N1 - The research described in this thesis was supported by Medisch Spectrum Twente, Hospital Group, Enschede, The Netherlands

    PY - 2007/6/8

    Y1 - 2007/6/8

    N2 - This thesis describes the process of the development towards a microfluidic platform to perform apoptosis studies on chip in real-time at a single-cell level. The requirements for such cell-based assays are discussed as well as the advantages of using microfluidics for cellular analysis. Our main interest is focused on breast cancer cells. Ultimately, this microfluidic chip has to function as a new analytical device for the clinic to provide patients with the best individual therapy.

    AB - This thesis describes the process of the development towards a microfluidic platform to perform apoptosis studies on chip in real-time at a single-cell level. The requirements for such cell-based assays are discussed as well as the advantages of using microfluidics for cellular analysis. Our main interest is focused on breast cancer cells. Ultimately, this microfluidic chip has to function as a new analytical device for the clinic to provide patients with the best individual therapy.

    KW - METIS-241707

    KW - EWI-10321

    KW - IR-57881

    M3 - PhD Thesis - Research UT, graduation UT

    SN - 978-90-365-2499-5

    PB - University of Twente

    CY - Zutphen

    ER -

    Wolbers F. Apoptosis chip for drug screening. Zutphen: University of Twente, 2007. 214 p.