TY - JOUR
T1 - Assessing the Microcirculation of the Foot with Laser Speckle Contrast Imaging During Endovascular and Hybrid Revascularisation Procedures in Patients with Chronic Limb Threatening Ischaemia
AU - Wermelink, Bryan
AU - Mennes, Onno A.
AU - Van Baal, Jeff G.
AU - Steenbergen, Wiendelt
AU - Geelkerken, Robert H.
AU - Aarnink, Saskia H.
AU - Beuk, Roland
AU - Brusse-Keiser, Marjolein
AU - Haalboom, Marieke
AU - Kruse, Rombout R.
AU - Manohar, Srirang
AU - Meerwaldt, Robbert
AU - Menting, Theo
AU - Reichman, Boudewijn L.
AU - Slart, Riemer H.J.A.
AU - Willigendael, Edith M.
AU - study group
N1 - Funding Information:
No conflicts of interest. This study was supported financially by an unrestricted research grant from the Pioneers in Health Care Innovation Fund, established by the University of Twente, Saxion University of Applied Sciences, Medisch Spectrum Twente, ZiekenhuisGroep Twente and Deventer Hospital. This project was funded by the TKI High Tech Systems and Materials (HTSM) via the Dutch Ministry of Economic Affairs and Climate Policy’s PPS bonus scheme for Research and Innovation. OAM: NWO domain Applied and Engineering Sciences, project 14538, and Diavasc Foundation.
PY - 2022/6
Y1 - 2022/6
N2 - In peripheral arterial disease the tissue microcirculation becomes impaired, ultimately resulting in chronic limb threatening ischaemia (CLTI) in 5% of cases. 1 CLTI prognosis is poor unless successful revascularisation is performed. 2 Endovascular and hybrid revascularisation procedures are performed under fluoroscopic and angiographic guidance to visualise the per-operative impact on the macrocirculation. Unfortunately, both lack the ability to visualise the impact on microcirculation, while restoring the microcirculation plays a pivotal role in CLTI. 3 By introducing additional per-operative assessment of the microcirculation, the impact of revascularisation on the microcirculation can be assessed in real time. This allows the surgical team to extend or adjust the revascularisation procedure in a timely manner, improving (prediction of) the clinical outcome.
AB - In peripheral arterial disease the tissue microcirculation becomes impaired, ultimately resulting in chronic limb threatening ischaemia (CLTI) in 5% of cases. 1 CLTI prognosis is poor unless successful revascularisation is performed. 2 Endovascular and hybrid revascularisation procedures are performed under fluoroscopic and angiographic guidance to visualise the per-operative impact on the macrocirculation. Unfortunately, both lack the ability to visualise the impact on microcirculation, while restoring the microcirculation plays a pivotal role in CLTI. 3 By introducing additional per-operative assessment of the microcirculation, the impact of revascularisation on the microcirculation can be assessed in real time. This allows the surgical team to extend or adjust the revascularisation procedure in a timely manner, improving (prediction of) the clinical outcome.
KW - Chronic limb threatening ischaemia
KW - Endovascular revascularisation
KW - Laser speckle contrast imaging
KW - Microcirculation
KW - Peripheral arterial occlusive disease
KW - 22/3 OA procedure
UR - http://www.scopus.com/inward/record.url?scp=85134312020&partnerID=8YFLogxK
U2 - 10.1016/j.ejvs.2022.03.036
DO - 10.1016/j.ejvs.2022.03.036
M3 - Letter
C2 - 35739040
AN - SCOPUS:85134312020
SN - 1078-5884
VL - 63
SP - 898
EP - 899
JO - European journal of vascular and endovascular surgery
JF - European journal of vascular and endovascular surgery
IS - 6
ER -