Atom sharp needles, the missing link in microneedle drug delivery

J. Wissink; Johan W. Berenschot; Niels Roelof Tas

Atom sharp needles, the missing link in microneedle drug delivery

J. Wissink, Johan W. Berenschot, Niels Roelof Tas

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic

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Abstract

The skin barrier function is a major challenge for delivery of drugs via the skin. Located in the outermost layer of the skin, the stratum corneum (SC) consists of dead cells embedded in lipid regions, only 10-20 microm thick, tough but flexible and elastic. Hyperdermic needles penetrate the skin succesfully, but nerve rich tissue in the lower skin is penetrated which is simply painfull

Original language	Undefined
Title of host publication	Proceedings of Medical Devices Conference
Place of Publication	Kopenhagen
Publisher	Medical Devices Committee
Pages	23-26
Number of pages	4
ISBN (Print)	not assigned
Publication status	Published - 6 Oct 2008
Event	Medical Devices Conference 2008 - Kopenhagen, Denmark Duration: 6 Oct 2008 → 6 Oct 2008

Publication series

Name
Publisher	Medical Devices Committee

Conference

Conference	Medical Devices Conference 2008
Country/Territory	Denmark
City	Kopenhagen
Period	6/10/08 → 6/10/08

Keywords

EWI-14700
METIS-255874
IR-65249

Access to Document

Cite this

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title = "Atom sharp needles, the missing link in microneedle drug delivery",

abstract = "The skin barrier function is a major challenge for delivery of drugs via the skin. Located in the outermost layer of the skin, the stratum corneum (SC) consists of dead cells embedded in lipid regions, only 10-20 microm thick, tough but flexible and elastic. Hyperdermic needles penetrate the skin succesfully, but nerve rich tissue in the lower skin is penetrated which is simply painfull",

keywords = "EWI-14700, METIS-255874, IR-65249",

author = "J. Wissink and Berenschot, {Johan W.} and Tas, {Niels Roelof}",

year = "2008",

month = oct,

day = "6",

language = "Undefined",

isbn = "not assigned",

publisher = "Medical Devices Committee",

pages = "23--26",

booktitle = "Proceedings of Medical Devices Conference",

note = "Medical Devices Conference 2008 ; Conference date: 06-10-2008 Through 06-10-2008",

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TY - GEN

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AU - Wissink, J.

AU - Berenschot, Johan W.

AU - Tas, Niels Roelof

PY - 2008/10/6

Y1 - 2008/10/6

N2 - The skin barrier function is a major challenge for delivery of drugs via the skin. Located in the outermost layer of the skin, the stratum corneum (SC) consists of dead cells embedded in lipid regions, only 10-20 microm thick, tough but flexible and elastic. Hyperdermic needles penetrate the skin succesfully, but nerve rich tissue in the lower skin is penetrated which is simply painfull

AB - The skin barrier function is a major challenge for delivery of drugs via the skin. Located in the outermost layer of the skin, the stratum corneum (SC) consists of dead cells embedded in lipid regions, only 10-20 microm thick, tough but flexible and elastic. Hyperdermic needles penetrate the skin succesfully, but nerve rich tissue in the lower skin is penetrated which is simply painfull

KW - EWI-14700

KW - METIS-255874

KW - IR-65249

M3 - Conference contribution

SN - not assigned

SP - 23

EP - 26

BT - Proceedings of Medical Devices Conference

PB - Medical Devices Committee

CY - Kopenhagen

T2 - Medical Devices Conference 2008

Y2 - 6 October 2008 through 6 October 2008

ER -