Azacalixphyrins as NIR photoacoustic contrast agents

Lucien Lavaud, Simon Pascal*, Khaled Metwally, Damien Gasteau, Anabela Da Silva, Zhongrui Chen, Mourad Elhabiri, Gabriel Canard, Denis Jacquemin, Olivier Siri

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)


Near-infrared (NIR) azacalixphyrins bearing aryl substituents strongly impacting the physico-chemical properties of the macrocycles were designed, enabling hyperchromic and bathochromic shifts of the absorption compared to their N-alkylated analogues. This engineering enhances the photoacoustic response under NIR excitation, making azacalixphyrins promising organic contrast agents that reach the 800-1000 nm range.

Original languageEnglish
Pages (from-to)12365-12368
Number of pages4
JournalChemical communications
Issue number87
Publication statusPublished - 1 Jan 2018
Externally publishedYes


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