Background free CARS imaging by local phase detection

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

1 Citation (Scopus)
6 Downloads (Pure)

Abstract

In this article we show that heterodyne CARS, based on a controlled and stable phase-preserving chain, can be used to measure amplitude and phase information of molecular vibration modes. The technique is validated by a comparison of the imaginary part of the heterodyne CARS spectrum to the spontaneous Raman spectrum of polyethylene. The detection of the phase allows for rejection of the non-resonant background from the data. The resulting improvement of the signal to noise ratio is shown by measurements on a sample containing lipid.
Original languageEnglish
Title of host publicationMultiphoton Microscopy in the Biomedical Sciences IX
EditorsAmmasi Periasamy, Peter T.C. So
Place of PublicationSan Jose, CA
PublisherSPIE
ISBN (Print)9780819474292
DOIs
Publication statusPublished - 2009
EventSPIE International Symposium on Biomedical Optics, BIOS 2009 - San Jose, United States
Duration: 24 Jan 200929 Jan 2009

Publication series

NameProceedings of SPIE
PublisherSPIE
Volume7183
ISSN (Print)1605-7422

Conference

ConferenceSPIE International Symposium on Biomedical Optics, BIOS 2009
Country/TerritoryUnited States
CitySan Jose
Period24/01/0929/01/09

Keywords

  • Coherent anti-Stokes Raman scattering
  • Microscopy
  • Nonlinear optics
  • Spectroscopy
  • Phase detection
  • Heterodyne

Fingerprint

Dive into the research topics of 'Background free CARS imaging by local phase detection'. Together they form a unique fingerprint.

Cite this