Background free CARS imaging by local phase detection

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

1 Citation (Scopus)

Abstract

In this article we show that heterodyne CARS, based on a controlled and stable phase-preserving chain, can be used to measure amplitude and phase information of molecular vibration modes. The technique is validated by a comparison of the imaginary part of the heterodyne CARS spectrum to the spontaneous Raman spectrum of polyethylene. The detection of the phase allows for rejection of the non-resonant background from the data. The resulting improvement of the signal to noise ratio is shown by measurements on a sample containing lipid.
Original languageUndefined
Title of host publicationMultiphoton microscopy in the biomedical sciences IX
EditorsAmmasi Periasamy, Peter T.C. So
PublisherSPIE
Pages718310
ISBN (Print)9780819474292
DOIs
Publication statusPublished - 2009

Publication series

NameProceedings of SPIE
PublisherSPIE
Volume7183
ISSN (Print)1605-7422

Keywords

  • IR-72659
  • Coherent anti-Stokes Raman scattering
  • Microscopy
  • Nonlinear optics
  • Spectroscopy
  • Phase detection
  • heterodyne

Cite this

Jurna, M., Korterik, J. P., Otto, C., Herek, J. L., & Offerhaus, H. L. (2009). Background free CARS imaging by local phase detection. In A. Periasamy, & P. T. C. So (Eds.), Multiphoton microscopy in the biomedical sciences IX (pp. 718310). (Proceedings of SPIE; Vol. 7183). SPIE. https://doi.org/10.1117/12.807714
Jurna, M. ; Korterik, Jeroen P. ; Otto, Cornelis ; Herek, Jennifer Lynn ; Offerhaus, Herman L. / Background free CARS imaging by local phase detection. Multiphoton microscopy in the biomedical sciences IX. editor / Ammasi Periasamy ; Peter T.C. So. SPIE, 2009. pp. 718310 (Proceedings of SPIE).
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abstract = "In this article we show that heterodyne CARS, based on a controlled and stable phase-preserving chain, can be used to measure amplitude and phase information of molecular vibration modes. The technique is validated by a comparison of the imaginary part of the heterodyne CARS spectrum to the spontaneous Raman spectrum of polyethylene. The detection of the phase allows for rejection of the non-resonant background from the data. The resulting improvement of the signal to noise ratio is shown by measurements on a sample containing lipid.",
keywords = "IR-72659, Coherent anti-Stokes Raman scattering, Microscopy, Nonlinear optics, Spectroscopy, Phase detection, heterodyne",
author = "M. Jurna and Korterik, {Jeroen P.} and Cornelis Otto and Herek, {Jennifer Lynn} and Offerhaus, {Herman L.}",
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Jurna, M, Korterik, JP, Otto, C, Herek, JL & Offerhaus, HL 2009, Background free CARS imaging by local phase detection. in A Periasamy & PTC So (eds), Multiphoton microscopy in the biomedical sciences IX. Proceedings of SPIE, vol. 7183, SPIE, pp. 718310. https://doi.org/10.1117/12.807714

Background free CARS imaging by local phase detection. / Jurna, M.; Korterik, Jeroen P.; Otto, Cornelis; Herek, Jennifer Lynn; Offerhaus, Herman L.

Multiphoton microscopy in the biomedical sciences IX. ed. / Ammasi Periasamy; Peter T.C. So. SPIE, 2009. p. 718310 (Proceedings of SPIE; Vol. 7183).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

TY - CHAP

T1 - Background free CARS imaging by local phase detection

AU - Jurna, M.

AU - Korterik, Jeroen P.

AU - Otto, Cornelis

AU - Herek, Jennifer Lynn

AU - Offerhaus, Herman L.

PY - 2009

Y1 - 2009

N2 - In this article we show that heterodyne CARS, based on a controlled and stable phase-preserving chain, can be used to measure amplitude and phase information of molecular vibration modes. The technique is validated by a comparison of the imaginary part of the heterodyne CARS spectrum to the spontaneous Raman spectrum of polyethylene. The detection of the phase allows for rejection of the non-resonant background from the data. The resulting improvement of the signal to noise ratio is shown by measurements on a sample containing lipid.

AB - In this article we show that heterodyne CARS, based on a controlled and stable phase-preserving chain, can be used to measure amplitude and phase information of molecular vibration modes. The technique is validated by a comparison of the imaginary part of the heterodyne CARS spectrum to the spontaneous Raman spectrum of polyethylene. The detection of the phase allows for rejection of the non-resonant background from the data. The resulting improvement of the signal to noise ratio is shown by measurements on a sample containing lipid.

KW - IR-72659

KW - Coherent anti-Stokes Raman scattering

KW - Microscopy

KW - Nonlinear optics

KW - Spectroscopy

KW - Phase detection

KW - heterodyne

U2 - 10.1117/12.807714

DO - 10.1117/12.807714

M3 - Chapter

SN - 9780819474292

T3 - Proceedings of SPIE

SP - 718310

BT - Multiphoton microscopy in the biomedical sciences IX

A2 - Periasamy, Ammasi

A2 - So, Peter T.C.

PB - SPIE

ER -

Jurna M, Korterik JP, Otto C, Herek JL, Offerhaus HL. Background free CARS imaging by local phase detection. In Periasamy A, So PTC, editors, Multiphoton microscopy in the biomedical sciences IX. SPIE. 2009. p. 718310. (Proceedings of SPIE). https://doi.org/10.1117/12.807714