Bidirectional microfluidic pumping using an array of magnetic Janus microspheres rotating around magnetic disks

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    10 Citations (Scopus)

    Abstract

    We demonstrate a novel, flexible and programmable method to pump liquid through microchannels in lab-on-a-chip systems without the use of an external pump. The pumping principle is based on the rotation of ferromagnetic Janus microspheres around permalloy disks, driven by an external rotating magnetic field. By placing the disks close to the edge of the microchannel, a pumping rate of at least 0.3 nL/min was measured using tracking microspheres. Geometric programming of the pumping direction is possible by positioning the magnetic disk close to the side wall. A second degree of freedom in pumping direction is offered by the rotation direction of the external magnetic field. The method is especially suited for flow-controlled recirculation of chemical and biological species in microchannel applications - for example medium recirculation in culture chambers - opening the way towards novel, portable, on-chip applications without the need for external fluidic or electrical connections.
    Original languageUndefined
    Pages (from-to)2872-2878
    Number of pages7
    JournalLab on a chip
    Volume15
    DOIs
    Publication statusPublished - 8 Jul 2015

    Keywords

    • EWI-25982
    • METIS-312582
    • IR-95809

    Cite this

    @article{2d5ae96f91a943d4a4532bde997ac341,
    title = "Bidirectional microfluidic pumping using an array of magnetic Janus microspheres rotating around magnetic disks",
    abstract = "We demonstrate a novel, flexible and programmable method to pump liquid through microchannels in lab-on-a-chip systems without the use of an external pump. The pumping principle is based on the rotation of ferromagnetic Janus microspheres around permalloy disks, driven by an external rotating magnetic field. By placing the disks close to the edge of the microchannel, a pumping rate of at least 0.3 nL/min was measured using tracking microspheres. Geometric programming of the pumping direction is possible by positioning the magnetic disk close to the side wall. A second degree of freedom in pumping direction is offered by the rotation direction of the external magnetic field. The method is especially suited for flow-controlled recirculation of chemical and biological species in microchannel applications - for example medium recirculation in culture chambers - opening the way towards novel, portable, on-chip applications without the need for external fluidic or electrical connections.",
    keywords = "EWI-25982, METIS-312582, IR-95809",
    author = "{van den Beld}, {Wesley Theodorus Eduardus} and N.L. Cadena and Bomer, {Johan G.} and {de Weerd}, {Eddy L} and Leon Abelmann and {van den Berg}, Albert and Eijkel, {Jan C.T.}",
    note = "eemcs-eprint-25982",
    year = "2015",
    month = "7",
    day = "8",
    doi = "10.1039/C5LC00199D",
    language = "Undefined",
    volume = "15",
    pages = "2872--2878",
    journal = "Lab on a chip",
    issn = "1473-0197",
    publisher = "Royal Society of Chemistry",

    }

    TY - JOUR

    T1 - Bidirectional microfluidic pumping using an array of magnetic Janus microspheres rotating around magnetic disks

    AU - van den Beld, Wesley Theodorus Eduardus

    AU - Cadena, N.L.

    AU - Bomer, Johan G.

    AU - de Weerd, Eddy L

    AU - Abelmann, Leon

    AU - van den Berg, Albert

    AU - Eijkel, Jan C.T.

    N1 - eemcs-eprint-25982

    PY - 2015/7/8

    Y1 - 2015/7/8

    N2 - We demonstrate a novel, flexible and programmable method to pump liquid through microchannels in lab-on-a-chip systems without the use of an external pump. The pumping principle is based on the rotation of ferromagnetic Janus microspheres around permalloy disks, driven by an external rotating magnetic field. By placing the disks close to the edge of the microchannel, a pumping rate of at least 0.3 nL/min was measured using tracking microspheres. Geometric programming of the pumping direction is possible by positioning the magnetic disk close to the side wall. A second degree of freedom in pumping direction is offered by the rotation direction of the external magnetic field. The method is especially suited for flow-controlled recirculation of chemical and biological species in microchannel applications - for example medium recirculation in culture chambers - opening the way towards novel, portable, on-chip applications without the need for external fluidic or electrical connections.

    AB - We demonstrate a novel, flexible and programmable method to pump liquid through microchannels in lab-on-a-chip systems without the use of an external pump. The pumping principle is based on the rotation of ferromagnetic Janus microspheres around permalloy disks, driven by an external rotating magnetic field. By placing the disks close to the edge of the microchannel, a pumping rate of at least 0.3 nL/min was measured using tracking microspheres. Geometric programming of the pumping direction is possible by positioning the magnetic disk close to the side wall. A second degree of freedom in pumping direction is offered by the rotation direction of the external magnetic field. The method is especially suited for flow-controlled recirculation of chemical and biological species in microchannel applications - for example medium recirculation in culture chambers - opening the way towards novel, portable, on-chip applications without the need for external fluidic or electrical connections.

    KW - EWI-25982

    KW - METIS-312582

    KW - IR-95809

    U2 - 10.1039/C5LC00199D

    DO - 10.1039/C5LC00199D

    M3 - Article

    VL - 15

    SP - 2872

    EP - 2878

    JO - Lab on a chip

    JF - Lab on a chip

    SN - 1473-0197

    ER -