Biodegradable multiblock copolymers for drug delivery applications

Riemke van Dijkhuizen-Radersma

Research output: ThesisPhD Thesis - Research external, graduation UTAcademic

16 Downloads (Pure)

Abstract

With rapid advances in genomic research and biotechnology, an increasing number of pharmaceutical proteins and peptides become available for a variety of diseases. However, the efficient delivery of these drugs is hampered by their large size and (biological) instability. Consequently, to obtain a desired therapeutic effect, proteins and peptides are usually administered parenterally by repeated subcutaneous or intramuscular injection. To overcome the problem of patient compliance, extensive research is performed on the development of controlled release systems.
Original languageEnglish
Awarding Institution
  • University of Twente
Supervisors/Advisors
  • de Groot, K., Supervisor
  • van Blitterswijk, C.A., Supervisor
  • Bezemer, J.M., Co-Supervisor
Award date2 Jul 2004
Place of PublicationEnschede
Publisher
Print ISBNs90-365-2055-X
Publication statusPublished - 2 Jul 2004

Fingerprint

Drug delivery
Copolymers
Peptides
Biotechnology
Pharmaceutical Preparations
Proteins
Compliance

Keywords

  • METIS-223541
  • IR-41555

Cite this

van Dijkhuizen-Radersma, R. (2004). Biodegradable multiblock copolymers for drug delivery applications. Enschede: Universiteit Twente.
van Dijkhuizen-Radersma, Riemke. / Biodegradable multiblock copolymers for drug delivery applications. Enschede : Universiteit Twente, 2004. 217 p.
@phdthesis{f8d058ae2c6a4d6cb72c45f40f321a82,
title = "Biodegradable multiblock copolymers for drug delivery applications",
abstract = "With rapid advances in genomic research and biotechnology, an increasing number of pharmaceutical proteins and peptides become available for a variety of diseases. However, the efficient delivery of these drugs is hampered by their large size and (biological) instability. Consequently, to obtain a desired therapeutic effect, proteins and peptides are usually administered parenterally by repeated subcutaneous or intramuscular injection. To overcome the problem of patient compliance, extensive research is performed on the development of controlled release systems.",
keywords = "METIS-223541, IR-41555",
author = "{van Dijkhuizen-Radersma}, Riemke",
year = "2004",
month = "7",
day = "2",
language = "English",
isbn = "90-365-2055-X",
publisher = "Universiteit Twente",
school = "University of Twente",

}

van Dijkhuizen-Radersma, R 2004, 'Biodegradable multiblock copolymers for drug delivery applications', University of Twente, Enschede.

Biodegradable multiblock copolymers for drug delivery applications. / van Dijkhuizen-Radersma, Riemke.

Enschede : Universiteit Twente, 2004. 217 p.

Research output: ThesisPhD Thesis - Research external, graduation UTAcademic

TY - THES

T1 - Biodegradable multiblock copolymers for drug delivery applications

AU - van Dijkhuizen-Radersma, Riemke

PY - 2004/7/2

Y1 - 2004/7/2

N2 - With rapid advances in genomic research and biotechnology, an increasing number of pharmaceutical proteins and peptides become available for a variety of diseases. However, the efficient delivery of these drugs is hampered by their large size and (biological) instability. Consequently, to obtain a desired therapeutic effect, proteins and peptides are usually administered parenterally by repeated subcutaneous or intramuscular injection. To overcome the problem of patient compliance, extensive research is performed on the development of controlled release systems.

AB - With rapid advances in genomic research and biotechnology, an increasing number of pharmaceutical proteins and peptides become available for a variety of diseases. However, the efficient delivery of these drugs is hampered by their large size and (biological) instability. Consequently, to obtain a desired therapeutic effect, proteins and peptides are usually administered parenterally by repeated subcutaneous or intramuscular injection. To overcome the problem of patient compliance, extensive research is performed on the development of controlled release systems.

KW - METIS-223541

KW - IR-41555

M3 - PhD Thesis - Research external, graduation UT

SN - 90-365-2055-X

PB - Universiteit Twente

CY - Enschede

ER -

van Dijkhuizen-Radersma R. Biodegradable multiblock copolymers for drug delivery applications. Enschede: Universiteit Twente, 2004. 217 p.