Biological characterisation of tissue-engineered vascular grafts

Paula Engbers-Buijtenhuijs

Biological characterisation of tissue-engineered vascular grafts

Paula Engbers-Buijtenhuijs

Biomaterials Science and Technology

Research output: Thesis › PhD Thesis - Research UT, graduation UT

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Abstract

This thesis describes the development of tissue-engineered (TE) autologous vascular prostheses, exclusively composed of biological materials and vascular cells, especially for small-diameter applications. A TE construct mimicking the media (middle layer) of a natural blood vessel in terms of morphology, mechanical strength 1 and appropriate cellular functions was produced. In addition, several methods to evaluate tissue homeostasis in the TE constructs were investigated.

Original language	English
Awarding Institution	University of Twente
Supervisors/Advisors	Vermes, I., Supervisor Feijen, J., Supervisor Poot, A.A., Co-Supervisor
Award date	1 Apr 2005
Place of Publication	Enschede
Publisher	University of Twente
Print ISBNs	90-365-2163-7
Publication status	Published - 1 Apr 2005

Keywords

METIS-224365
IR-50435

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title = "Biological characterisation of tissue-engineered vascular grafts",

abstract = "This thesis describes the development of tissue-engineered (TE) autologous vascular prostheses, exclusively composed of biological materials and vascular cells, especially for small-diameter applications. A TE construct mimicking the media (middle layer) of a natural blood vessel in terms of morphology, mechanical strength 1 and appropriate cellular functions was produced. In addition, several methods to evaluate tissue homeostasis in the TE constructs were investigated.",

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AB - This thesis describes the development of tissue-engineered (TE) autologous vascular prostheses, exclusively composed of biological materials and vascular cells, especially for small-diameter applications. A TE construct mimicking the media (middle layer) of a natural blood vessel in terms of morphology, mechanical strength 1 and appropriate cellular functions was produced. In addition, several methods to evaluate tissue homeostasis in the TE constructs were investigated.

KW - METIS-224365

KW - IR-50435

M3 - PhD Thesis - Research UT, graduation UT

SN - 90-365-2163-7

PB - University of Twente

CY - Enschede

ER -

Biological characterisation of tissue-engineered vascular grafts

Abstract

Keywords

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