Biomolecular sensing using surface micromachined silicon plates

A.M. Zapata; E.T. Carlen; E.S. Kim; J. Hsiao; D. Traviglia; M.S. Weinberg

doi:10.1109/SENSOR.2007.4300259

Biomolecular sensing using surface micromachined silicon plates

A.M. Zapata
, E.T. Carlen
, E.S. Kim
, J. Hsiao
, D. Traviglia
, M.S. Weinberg

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

4 Citations (Scopus)

213 Downloads (Pure)

Abstract

Micromachined sensors to detect surface stress changes associated with interactions between an immobilized chemically selective receptor and a target analyte are presented. The top isolated sensing surface of a free-standing silicon plate is prepared with a thin Au layer, followed by a covalent attachment of chemical or biomolecule forming a chemically-selective surface. Surface stress changes in air are measured capacitively due to the formation of an alkanethiol self-assembled monolayer (SAM). Detection of biomolecular binding in liquid samples is measured optically using the streptavidin-biotin complex and AM. tuberculosis antigen-antibody system used for clinical tuberculosis (TB) diagnosis.

Original language	English
Title of host publication	TRANSDUCERS 2007 - International Solid-State Sensors, Actuators and Microsystems Conference
Editors	G. Delapierre, R. Puers
Place of Publication	Piscataway, NJ
Publisher	IEEE
Pages	831-834
Number of pages	4
ISBN (Electronic)	1-4244-0842-3 (CD)
ISBN (Print)	1-4244-0841-5
DOIs	https://doi.org/10.1109/SENSOR.2007.4300259
Publication status	Published - 10 Jun 2007
Event	14th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS 2007 - Lyon, France Duration: 10 Jun 2007 → 14 Jun 2007 Conference number: 14

Publication series

Name	Proceedings of TRANSDUCERS - International Solid-State Sensors, Actuators and Microsystems Conference
Publisher	IEEE Computer Society
Volume	2007
ISSN (Print)	2159-547X
ISSN (Electronic)	2164-1641

Conference

Conference	14th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS 2007
Abbreviated title	TRANSDUCERS 2007
Country/Territory	France
City	Lyon
Period	10/06/07 → 14/06/07

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

n/a OA procedure

Access to Document

10.1109/SENSOR.2007.4300259

Cite this

Zapata, A. M., Carlen, E. T., Kim, E. S., Hsiao, J., Traviglia, D., & Weinberg, M. S. (2007). Biomolecular sensing using surface micromachined silicon plates. In G. Delapierre, & R. Puers (Eds.), TRANSDUCERS 2007 - International Solid-State Sensors, Actuators and Microsystems Conference (pp. 831-834). (Proceedings of TRANSDUCERS - International Solid-State Sensors, Actuators and Microsystems Conference; Vol. 2007). IEEE. https://doi.org/10.1109/SENSOR.2007.4300259

Zapata, A.M. ; Carlen, E.T. ; Kim, E.S. et al. / Biomolecular sensing using surface micromachined silicon plates. TRANSDUCERS 2007 - International Solid-State Sensors, Actuators and Microsystems Conference. editor / G. Delapierre ; R. Puers. Piscataway, NJ : IEEE, 2007. pp. 831-834 (Proceedings of TRANSDUCERS - International Solid-State Sensors, Actuators and Microsystems Conference).

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title = "Biomolecular sensing using surface micromachined silicon plates",

abstract = "Micromachined sensors to detect surface stress changes associated with interactions between an immobilized chemically selective receptor and a target analyte are presented. The top isolated sensing surface of a free-standing silicon plate is prepared with a thin Au layer, followed by a covalent attachment of chemical or biomolecule forming a chemically-selective surface. Surface stress changes in air are measured capacitively due to the formation of an alkanethiol self-assembled monolayer (SAM). Detection of biomolecular binding in liquid samples is measured optically using the streptavidin-biotin complex and AM. tuberculosis antigen-antibody system used for clinical tuberculosis (TB) diagnosis.",

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author = "A.M. Zapata and E.T. Carlen and E.S. Kim and J. Hsiao and D. Traviglia and M.S. Weinberg",

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Zapata, AM, Carlen, ET, Kim, ES, Hsiao, J, Traviglia, D & Weinberg, MS 2007, Biomolecular sensing using surface micromachined silicon plates. in G Delapierre & R Puers (eds), TRANSDUCERS 2007 - International Solid-State Sensors, Actuators and Microsystems Conference. Proceedings of TRANSDUCERS - International Solid-State Sensors, Actuators and Microsystems Conference, vol. 2007, IEEE, Piscataway, NJ, pp. 831-834, 14th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS 2007, Lyon, France, 10/06/07. https://doi.org/10.1109/SENSOR.2007.4300259

Biomolecular sensing using surface micromachined silicon plates. / Zapata, A.M.; Carlen, E.T.; Kim, E.S. et al.
TRANSDUCERS 2007 - International Solid-State Sensors, Actuators and Microsystems Conference. ed. / G. Delapierre; R. Puers. Piscataway, NJ: IEEE, 2007. p. 831-834 (Proceedings of TRANSDUCERS - International Solid-State Sensors, Actuators and Microsystems Conference; Vol. 2007).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

TY - GEN

T1 - Biomolecular sensing using surface micromachined silicon plates

AU - Zapata, A.M.

AU - Carlen, E.T.

AU - Kim, E.S.

AU - Hsiao, J.

AU - Traviglia, D.

AU - Weinberg, M.S.

N1 - Conference code: 14

PY - 2007/6/10

Y1 - 2007/6/10

N2 - Micromachined sensors to detect surface stress changes associated with interactions between an immobilized chemically selective receptor and a target analyte are presented. The top isolated sensing surface of a free-standing silicon plate is prepared with a thin Au layer, followed by a covalent attachment of chemical or biomolecule forming a chemically-selective surface. Surface stress changes in air are measured capacitively due to the formation of an alkanethiol self-assembled monolayer (SAM). Detection of biomolecular binding in liquid samples is measured optically using the streptavidin-biotin complex and AM. tuberculosis antigen-antibody system used for clinical tuberculosis (TB) diagnosis.

AB - Micromachined sensors to detect surface stress changes associated with interactions between an immobilized chemically selective receptor and a target analyte are presented. The top isolated sensing surface of a free-standing silicon plate is prepared with a thin Au layer, followed by a covalent attachment of chemical or biomolecule forming a chemically-selective surface. Surface stress changes in air are measured capacitively due to the formation of an alkanethiol self-assembled monolayer (SAM). Detection of biomolecular binding in liquid samples is measured optically using the streptavidin-biotin complex and AM. tuberculosis antigen-antibody system used for clinical tuberculosis (TB) diagnosis.

KW - n/a OA procedure

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M3 - Conference contribution

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EP - 834

BT - TRANSDUCERS 2007 - International Solid-State Sensors, Actuators and Microsystems Conference

A2 - Delapierre, G.

A2 - Puers, R.

PB - IEEE

CY - Piscataway, NJ

T2 - 14th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS 2007

Y2 - 10 June 2007 through 14 June 2007

ER -

Zapata AM, Carlen ET, Kim ES, Hsiao J, Traviglia D, Weinberg MS. Biomolecular sensing using surface micromachined silicon plates. In Delapierre G, Puers R, editors, TRANSDUCERS 2007 - International Solid-State Sensors, Actuators and Microsystems Conference. Piscataway, NJ: IEEE. 2007. p. 831-834. (Proceedings of TRANSDUCERS - International Solid-State Sensors, Actuators and Microsystems Conference). doi: 10.1109/SENSOR.2007.4300259

Biomolecular sensing using surface micromachined silicon plates

Abstract

Publication series

Conference

UN SDGs

Keywords

Access to Document

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