Block copolymers of poly(l-lactide) and poly(e-caprolactone) or poly(ethylene glycol) prepared by reactive extrusion

W.M. Stevels, A. Bernard, P. van de Witte, P.J. Dijkstra, J. Feijen

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Abstract

Blends of poly(L-lactide) (PLLA) and poly(-caprolactone) (PCL) were prepared in a co-rotating twin screw miniextruder (40 rpm, 200°). It was attempted to prepare multiblock copolymers by allowing a controlled number of transesterification reactions. Various cat-alysts (n-Bu3SnOMe, Sn(Oct)2, Ti(OBu)4, Y(Oct)3, para-toluene sulphonic acid) were introduced to promote these transesterification reactions. However, PLLA degradation by ring-closing depolymerization was the dominant reaction in every case. Alternatively, after showing that L-lactide can be conveniently polymerized in the extruder, L-lactide and hy-droxyl functionalized prepolymers of PCL or poly(ethylene glycol) (PEG) were fed to the extruder in the presence of stannous octoate. Monomer conversions of over 90% and effective transformation of all hydroxyl end groups present were generally reached. Di-and triblock copolymers could be prepared in this way with characteristics very similar to polymers prepared in a batch-type process, but with considerably reduced reaction times in a fashion, which is, in principle, scaleable to a continuous process for the production of such block copolymers.
Original languageEnglish
Pages (from-to)1295-1301
Number of pages7
JournalJournal of applied polymer science
Volume62
Issue number62
DOIs
Publication statusPublished - 1996

Keywords

  • METIS-105390
  • IR-71284

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