Blood Vessel Model using Tissue Modules with on-demand Stimuli

V. Trikalitis, N. Salehi Nik, J. Rouwkema

    Research output: Contribution to conferencePosterOther research output

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    Abstract

    Artificial vascularization of tissue has been a major barrier in the upscaling
    of tissue engineering. Achieving angiogenesis from a pre-existing vessel in
    a controlled manner is a possible solution to prevascularize tissue. Microfluidic
    approaches do not allow yet the creation of a complex hierarchical
    tissue construct that can be manipulated and removed from the creation
    template.Thus the challenge is to simulate angiogenesis in a 1:1 scale.
    We aim to assemble a blood vessel module that will include:
    on-demand flow, through a tubular structure comprised of endothelial
    cells, fibroblasts and smooth muscle cells suspended in a hydrogel
    environment functionalized with growth factors.
    Original languageEnglish
    Publication statusPublished - 28 Nov 2017
    EventThe Netherlands Society for Biomaterials and Tissue Engineering 26th Annual Meeting, 2017 - De Werelt Lunteren, Lunteren, Netherlands
    Duration: 29 Nov 201730 Nov 2017
    Conference number: 26
    http://nbte.nl/

    Conference

    ConferenceThe Netherlands Society for Biomaterials and Tissue Engineering 26th Annual Meeting, 2017
    Abbreviated titleNBTE 2017
    CountryNetherlands
    CityLunteren
    Period29/11/1730/11/17
    Internet address

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