Research output per year
Research output per year
Baris Imre*, Elina Thibeau-Sutre, Jorieke Reimer, Kuan Kho, Jelmer M. Wolterink
Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review
Chronic subdural hematoma (cSDH) is a common neurological condition characterized by the accumulation of blood between the brain and the dura mater. This accumulation of blood can exert pressure on the brain, potentially leading to fatal outcomes. Treatment options for cSDH are limited to invasive surgery or non-invasive management. Traditionally, the midline shift, hand-measured by experts from an ideal sagittal plane, and the hematoma volume have been the primary metrics for quantifying and analyzing cSDH. However, these approaches do not quantify the local 3D brain deformation caused by cSDH. We propose a novel method using anatomy-aware unsupervised diffeomorphic pseudo-healthy synthesis to generate brain deformation fields. The deformation fields derived from this process are utilized to extract biomarkers that quantify the shift in the brain due to cSDH. We use CT scans of 121 patients for training and validation of our method and find that our metrics allow the identification of patients who require surgery. Our results indicate that automatically obtained brain deformation fields might contain prognostic value for personalized cSDH treatment. Our implementation is available on: https://github.com/MIAGroupUT/Brain-Shift
Original language | English |
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Title of host publication | Medical Image Computing and Computer Assisted Intervention – MICCAI 2024 - 27th International Conference, Proceedings |
Editors | Marius George Linguraru, Qi Dou, Aasa Feragen, Stamatia Giannarou, Ben Glocker, Karim Lekadir, Julia A. Schnabel |
Publisher | Springer |
Pages | 34-44 |
Number of pages | 11 |
ISBN (Print) | 9783031720680 |
DOIs | |
Publication status | Published - 4 Oct 2024 |
Event | 27th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2024 - Marrakesh, Morocco Duration: 6 Oct 2024 → 10 Oct 2024 Conference number: 27 |
Name | Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) |
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Volume | 15002 LNCS |
ISSN (Print) | 0302-9743 |
ISSN (Electronic) | 1611-3349 |
Conference | 27th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2024 |
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Abbreviated title | MICCAI 2024 |
Country/Territory | Morocco |
City | Marrakesh |
Period | 6/10/24 → 10/10/24 |
Research output: Working paper › Preprint › Academic