Calix[4]arenes as building blocks for molecular receptors

Jan-Dirk van Loon; Jan-Dirk van Loon; Jan F. Heida; Willem Verboom; David Reinhoudt

doi:10.1002/recl.19921110704

Calix[4]arenes as building blocks for molecular receptors

Jan-Dirk van Loon, Jan-Dirk van Loon, Jan F. Heida, Willem Verboom, David Reinhoudt

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Abstract

Molecular receptors for organic molecules are described in which calix[4]arene is used as a molecular platform rather than for its cavity. This is illustrated by the synthesis of a receptor for barbiturates, a calix[4]arene in a cone conformation containing two diaminotriazine moieties at the upper rim. This receptor (9) forms a molecular cleft in which phenobarbital complexes by hydrogen bonding both triazine rings. The association constant K is 520 M 1, when the self-association of the barbiturate is taken into account.

Original language	English
Pages (from-to)	353-359
Number of pages	7
Journal	Recueil des travaux chimiques des Pays-Bas
Volume	111
Issue number	7-8
DOIs	https://doi.org/10.1002/recl.19921110704
Publication status	Published - 1992

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10.1002/recl.19921110704

VanLoon1992calixFinal published version, 694 KB

1 Poster
1 PhD Thesis - Research UT, graduation UT

Calix[4]arenes as building blocks for molecular receptors
van Loon, J.-D., 3 Apr 1992, Enschede. 169 p.
Research output: Thesis › PhD Thesis - Research UT, graduation UT
Calix[4]arenes as building blocks for molecular receptors
van Loon, J.-D., Heida, J., Janssen, R. G., Verboom, W. & Reinhoudt, D., 1 Sept 1991. 1 p.
Research output: Contribution to conference › Poster › Other research output

Cite this

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AB - Molecular receptors for organic molecules are described in which calix[4]arene is used as a molecular platform rather than for its cavity. This is illustrated by the synthesis of a receptor for barbiturates, a calix[4]arene in a cone conformation containing two diaminotriazine moieties at the upper rim. This receptor (9) forms a molecular cleft in which phenobarbital complexes by hydrogen bonding both triazine rings. The association constant K is 520 M 1, when the self-association of the barbiturate is taken into account.

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DO - 10.1002/recl.19921110704

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ER -

Calix[4]arenes as building blocks for molecular receptors

Abstract

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