Thresholds are dependent on stimulus properties and are related to different mechanisms in the nociceptive system. Measuring multiple thresholds enables a detailed observation of peripheral and central nociceptive processing. In this study, a model of capsaicin defunctionalization was used to investigate the effect on multiple simultaneously measured electrical nociceptive perception thresholds.With the presented data, increased electrical perception thresholds were observed due to capsaicin. Furthermore, this study confirms that thresholds depend on stimulus parameters. These data can be used to build a mathematical model of the nociceptive system and be used to interpret nociceptive changes.
|Title of host publication||Pain in Europe VIII: the 8th Congress of European Federation of IASP Chapters (EFIC)|
|Place of Publication||Italy|
|Number of pages||1|
|ISBN (Print)||not assigned|
|Publication status||Published - Oct 2013|
|Event||Pain in Europe VIII 2013 - Fortezza da Basso, Florence, Italy|
Duration: 9 Oct 2013 → 12 Oct 2013
Conference number: 8
|Conference||Pain in Europe VIII 2013|
|Period||9/10/13 → 12/10/13|
- BSS-Central mechanisms underlying chronic pain
Doll, R., Buitenweg, J. R., van Amerongen, G., Hay, J. L., Groeneveld, G. J., & Veltink, P. H. (2013). Capsaicin (8%) patch increases multiple electrical nociceptive thresholds in healthy human subjects. In Pain in Europe VIII: the 8th Congress of European Federation of IASP Chapters (EFIC) (pp. 756-756). Italy: EFIC.