Capsaicin (8%) patch increases multiple electrical nociceptive thresholds in healthy human subjects

Robert Doll; Jan R. Buitenweg; G. van Amerongen; J.L. Hay; G.J. Groeneveld; P.H. Veltink

Capsaicin (8%) patch increases multiple electrical nociceptive thresholds in healthy human subjects

Robert Doll, Jan R. Buitenweg, G. van Amerongen, J.L. Hay, G.J. Groeneveld, P.H. Veltink

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic

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Abstract

Thresholds are dependent on stimulus properties and are related to different mechanisms in the nociceptive system. Measuring multiple thresholds enables a detailed observation of peripheral and central nociceptive processing. In this study, a model of capsaicin defunctionalization was used to investigate the effect on multiple simultaneously measured electrical nociceptive perception thresholds.With the presented data, increased electrical perception thresholds were observed due to capsaicin. Furthermore, this study confirms that thresholds depend on stimulus parameters. These data can be used to build a mathematical model of the nociceptive system and be used to interpret nociceptive changes.

Original language	English
Title of host publication	Pain in Europe VIII: the 8th Congress of European Federation of IASP Chapters (EFIC)
Place of Publication	Italy
Publisher	EFIC
Pages	756-756
Number of pages	1
Publication status	Published - Oct 2013
Event	Pain in Europe VIII 2013 - Fortezza da Basso, Florence, Italy Duration: 9 Oct 2013 → 12 Oct 2013 Conference number: 8

Conference

Conference	Pain in Europe VIII 2013
Country/Territory	Italy
City	Florence
Period	9/10/13 → 12/10/13

Keywords

BSS-Central mechanisms underlying chronic pain
threshold
Nociception
Pain
Psychophysics

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@inproceedings{e362c758ce164f84a30d09ffe20ae8a7,

title = "Capsaicin (8%) patch increases multiple electrical nociceptive thresholds in healthy human subjects",

abstract = "Thresholds are dependent on stimulus properties and are related to different mechanisms in the nociceptive system. Measuring multiple thresholds enables a detailed observation of peripheral and central nociceptive processing. In this study, a model of capsaicin defunctionalization was used to investigate the effect on multiple simultaneously measured electrical nociceptive perception thresholds.With the presented data, increased electrical perception thresholds were observed due to capsaicin. Furthermore, this study confirms that thresholds depend on stimulus parameters. These data can be used to build a mathematical model of the nociceptive system and be used to interpret nociceptive changes.",

keywords = "BSS-Central mechanisms underlying chronic pain, threshold, Nociception, Pain, Psychophysics",

author = "Robert Doll and Buitenweg, {Jan R.} and {van Amerongen}, G. and J.L. Hay and G.J. Groeneveld and P.H. Veltink",

year = "2013",

month = oct,

language = "English",

pages = "756--756",

booktitle = "Pain in Europe VIII: the 8th Congress of European Federation of IASP Chapters (EFIC)",

publisher = "EFIC",

note = "Pain in Europe VIII 2013 ; Conference date: 09-10-2013 Through 12-10-2013",

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Capsaicin (8%) patch increases multiple electrical nociceptive thresholds in healthy human subjects. / Doll, Robert; Buitenweg, Jan R.; van Amerongen, G. et al.

Pain in Europe VIII: the 8th Congress of European Federation of IASP Chapters (EFIC). Italy : EFIC, 2013. p. 756-756.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic

TY - GEN

T1 - Capsaicin (8%) patch increases multiple electrical nociceptive thresholds in healthy human subjects

AU - Doll, Robert

AU - Buitenweg, Jan R.

AU - van Amerongen, G.

AU - Hay, J.L.

AU - Groeneveld, G.J.

AU - Veltink, P.H.

N1 - Conference code: 8

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N2 - Thresholds are dependent on stimulus properties and are related to different mechanisms in the nociceptive system. Measuring multiple thresholds enables a detailed observation of peripheral and central nociceptive processing. In this study, a model of capsaicin defunctionalization was used to investigate the effect on multiple simultaneously measured electrical nociceptive perception thresholds.With the presented data, increased electrical perception thresholds were observed due to capsaicin. Furthermore, this study confirms that thresholds depend on stimulus parameters. These data can be used to build a mathematical model of the nociceptive system and be used to interpret nociceptive changes.

AB - Thresholds are dependent on stimulus properties and are related to different mechanisms in the nociceptive system. Measuring multiple thresholds enables a detailed observation of peripheral and central nociceptive processing. In this study, a model of capsaicin defunctionalization was used to investigate the effect on multiple simultaneously measured electrical nociceptive perception thresholds.With the presented data, increased electrical perception thresholds were observed due to capsaicin. Furthermore, this study confirms that thresholds depend on stimulus parameters. These data can be used to build a mathematical model of the nociceptive system and be used to interpret nociceptive changes.

KW - BSS-Central mechanisms underlying chronic pain

KW - threshold

KW - Nociception

KW - Pain

KW - Psychophysics

M3 - Conference contribution

SP - 756

EP - 756

BT - Pain in Europe VIII: the 8th Congress of European Federation of IASP Chapters (EFIC)

PB - EFIC

CY - Italy

T2 - Pain in Europe VIII 2013

Y2 - 9 October 2013 through 12 October 2013

ER -

Capsaicin (8%) patch increases multiple electrical nociceptive thresholds in healthy human subjects

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