Cascade reactions in an all-enzyme nanoreactor

Guillaume Delaittre, Irene C. Reynhout, Jeroen Johannes Lambertus Maria Cornelissen, Roeland J.M. Nolte

Research output: Contribution to journalArticleAcademicpeer-review

50 Citations (Scopus)


Good things come in small packages! Giant amphiphiles, consisting of a polymeric hydrophobic tail and a horseradish peroxidase head, were simultaneously synthesized and self-assembled into vesicles. During the self-assembly process, glucose oxidase was encapsulated to create enzymatic cascade nanoreactors (see picture; ABTS= 2,2′-azido-bis(3-ethylbenzthiazoline-6-sulfonic acid)).
Original languageUndefined
Pages (from-to)12600-12603
Number of pages4
JournalChemistry: a European journal
Issue number46
Publication statusPublished - 2009


  • cofactors
  • cascade reactions
  • vesicles
  • IR-72766
  • enzyme catalysis
  • METIS-263225
  • Bioconjugates

Cite this