Abstract
We report here on a microdevice for the spontaneous and simultaneous formation
of microtissues -or microscale spheroids- in a fast, controlled and reproducible way.
Spheroids are relevant constructs for tissue engineering applications, and notably for
studying the process of angiogenesis which is of crucial importance for both tissue
regeneration and understanding/manipulating tumor vascularization. Our microdevices
consist of PDMS microwell arrays whose surface properties are optimized
(PDMS composition and applied coating agent) for both promoting cellular aggregation
into spheroids and facilitating spheroid removal out of the device.
| Original language | English |
|---|---|
| Title of host publication | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
| Editors | L.E. Locascio, M. Gaitan, B.M. Paegel, D.J. Ross, W.N. Vreeland |
| Place of Publication | San Diego |
| Publisher | The Chemical and Biological Microsystems Society |
| Pages | 1165-1167 |
| Number of pages | 3 |
| ISBN (Print) | 978-0-9798064-1-4 |
| Publication status | Published - 12 Oct 2008 |
| Event | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2008 - San Diego, United States Duration: 12 Oct 2008 → 16 Oct 2008 Conference number: 12 |
Publication series
| Name | Micro Total Analysis Systems |
|---|---|
| Publisher | Chemical and Biological Micro Systems Society |
| Volume | 2 |
| ISSN (Print) | 1556-5890 |
Conference
| Conference | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2008 |
|---|---|
| Abbreviated title | MicroTAS |
| Country/Territory | United States |
| City | San Diego |
| Period | 12/10/08 → 16/10/08 |