A number of samples of poly(D,L-lactic acid) (PLA) with weight-average molecular weights Ṁw in the range 15,000-350,000 were prepared by a ring-opening polymerization. The molecular weight distributions (MWDs) of these samples were determined by gel permeation chromatography (GPC). The method involves a universal calibration of the columns on the basis of polystyrene standards and a rapid iteration algorithm leading to the establishment of the Mark-Houwink relationship. In addition, osmometry and viscometry data are presented. The effect of hydrolytic degradation on the MWD of two PLA samples was studied by GPC.
|Journal||Journal of Polymer Science: Polymer Chemistry Edition|
|Publication status||Published - 1983|
van Dijk, J. A. P. P., Smit, J. A. M., Kohn, F. E., & Feijen, J. (1983). Characterization of poly(D,L-lactic acid) by gel permeation chromatography. Journal of Polymer Science: Polymer Chemistry Edition, 21(1), 197-208. https://doi.org/10.1002/pol.1983.170210121