Characterization of the chemical composition of a block copolymer by liquid chromotography/mass spectroscopy using atomspheric pressure chemical ionization and electrospray ionization

S.M. van Leeuwen, B.H. Tan, Dirk W. Grijpma, Jan Feijen, U. Karst

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Liquid chromatography/mass spectrometry (LC/MS) with electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) in the positive and negative ion modes was used for the characterization of a block copolymer consisting of methoxy poly(ethylene oxide) (mPEO), an -caprolactone (CL) segment and linoleic acid (LA), used as surfactant in water-based latex paints. Chromatographic separation was obtained based on the number of CL units in the polymer species and the presence of an mPEO and/or LA tail. Different ionization methods were found to be complementary and only their combination allowed the qualitative profiling of the chemical composition. The LC/MS method has proven valuable for following the reaction in time, as well as for comparison of different polymeric surfactants.
Original languageUndefined
Pages (from-to)2629-2637
JournalRapid communications in mass spectrometry
Issue number16
Publication statusPublished - 2007


  • METIS-245515
  • IR-59867

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