Chemically modified field effect transistors: the effect of ion-pair association on the membrane potentials

P.L.H.M. Cobben, Peter L.H.M. Cobben, Richard J.M. Egberink, Johan G. Bomer, Piet Bergveld, David Reinhoudt

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    Abstract

    A theoretical model has been developed which relates physically accessible parameters to the formation of a membrane potential. The description is an extension of a theoretical description presented previously by our group, now including divalent cations and ion-pair association. Simulations of the overall membrane potential reveal several factors that may lead to non-Nernstian response curves. For monovalent and divalent cations a reduction in the slope of the response curve (sub-Nernstian response) should virtually always be expected when ion-pair association takes place in the membrane. Ion-pair association of divalent cations and sample anions can lead to a super-Nernstian response. A diffusion potential generally reduces the Nernstian slope of the response curve. In addition, several experimental results are described which illustrate and confirm our theoretical model.
    Original languageUndefined
    Pages (from-to)193-208
    JournalJournal of electroanalytical chemistry
    Volume368
    Issue number368
    DOIs
    Publication statusPublished - 1994

    Keywords

    • METIS-106615
    • IR-15069

    Cite this

    @article{bb84ef6399e54acda4a89c1547c78d17,
    title = "Chemically modified field effect transistors: the effect of ion-pair association on the membrane potentials",
    abstract = "A theoretical model has been developed which relates physically accessible parameters to the formation of a membrane potential. The description is an extension of a theoretical description presented previously by our group, now including divalent cations and ion-pair association. Simulations of the overall membrane potential reveal several factors that may lead to non-Nernstian response curves. For monovalent and divalent cations a reduction in the slope of the response curve (sub-Nernstian response) should virtually always be expected when ion-pair association takes place in the membrane. Ion-pair association of divalent cations and sample anions can lead to a super-Nernstian response. A diffusion potential generally reduces the Nernstian slope of the response curve. In addition, several experimental results are described which illustrate and confirm our theoretical model.",
    keywords = "METIS-106615, IR-15069",
    author = "P.L.H.M. Cobben and Cobben, {Peter L.H.M.} and Egberink, {Richard J.M.} and Bomer, {Johan G.} and Piet Bergveld and David Reinhoudt",
    year = "1994",
    doi = "10.1016/0022-0728(93)03114-5",
    language = "Undefined",
    volume = "368",
    pages = "193--208",
    journal = "Journal of electroanalytical chemistry",
    issn = "0368-1874",
    publisher = "Elsevier Sequoia",
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    }

    Chemically modified field effect transistors: the effect of ion-pair association on the membrane potentials. / Cobben, P.L.H.M.; Cobben, Peter L.H.M.; Egberink, Richard J.M.; Bomer, Johan G.; Bergveld, Piet; Reinhoudt, David.

    In: Journal of electroanalytical chemistry, Vol. 368, No. 368, 1994, p. 193-208.

    Research output: Contribution to journalArticleAcademicpeer-review

    TY - JOUR

    T1 - Chemically modified field effect transistors: the effect of ion-pair association on the membrane potentials

    AU - Cobben, P.L.H.M.

    AU - Cobben, Peter L.H.M.

    AU - Egberink, Richard J.M.

    AU - Bomer, Johan G.

    AU - Bergveld, Piet

    AU - Reinhoudt, David

    PY - 1994

    Y1 - 1994

    N2 - A theoretical model has been developed which relates physically accessible parameters to the formation of a membrane potential. The description is an extension of a theoretical description presented previously by our group, now including divalent cations and ion-pair association. Simulations of the overall membrane potential reveal several factors that may lead to non-Nernstian response curves. For monovalent and divalent cations a reduction in the slope of the response curve (sub-Nernstian response) should virtually always be expected when ion-pair association takes place in the membrane. Ion-pair association of divalent cations and sample anions can lead to a super-Nernstian response. A diffusion potential generally reduces the Nernstian slope of the response curve. In addition, several experimental results are described which illustrate and confirm our theoretical model.

    AB - A theoretical model has been developed which relates physically accessible parameters to the formation of a membrane potential. The description is an extension of a theoretical description presented previously by our group, now including divalent cations and ion-pair association. Simulations of the overall membrane potential reveal several factors that may lead to non-Nernstian response curves. For monovalent and divalent cations a reduction in the slope of the response curve (sub-Nernstian response) should virtually always be expected when ion-pair association takes place in the membrane. Ion-pair association of divalent cations and sample anions can lead to a super-Nernstian response. A diffusion potential generally reduces the Nernstian slope of the response curve. In addition, several experimental results are described which illustrate and confirm our theoretical model.

    KW - METIS-106615

    KW - IR-15069

    U2 - 10.1016/0022-0728(93)03114-5

    DO - 10.1016/0022-0728(93)03114-5

    M3 - Article

    VL - 368

    SP - 193

    EP - 208

    JO - Journal of electroanalytical chemistry

    JF - Journal of electroanalytical chemistry

    SN - 0368-1874

    IS - 368

    ER -