Chiral four-membered cyclic nitrones; asymmetric induction in the (4+2)-cycloaddition reaction of chiral ynamines and nitroalkenes

P.A. van Elburg, G.W.N. Honig, David Reinhoudt

Research output: Contribution to journalArticleAcademic

16 Citations (Scopus)
56 Downloads (Pure)

Abstract

Chiral four-membered cyclic nitrones were synthesized by the asymmetric (4+2)-cycloaddition of nitroalkenes 1 and chiral ynamines 2. The subsequent stereoselective addition of nucleophiles to these nitrones enabled the synthesis of chiral N-hydroxyazetidines.
Original languageUndefined
Pages (from-to)6397-6400
JournalTetrahedron letters
Volume28
Issue number50
DOIs
Publication statusPublished - 1987

Keywords

  • IR-69889

Cite this