Chirurgische decompressie bij het ruimte-innemende herseninfarct; aanmelding voor een gerandomiseerde trial

J. Hofmeijer; H. B. Van Der Worp; G. J. Amelink; A. Algra; J. Van Gijn; L. J. Kappelle

Chirurgische decompressie bij het ruimte-innemende herseninfarct; aanmelding voor een gerandomiseerde trial

Translated title of the contribution: Surgical decompression in space-occupying cerebral infarct; notification of a randomised trial

J. Hofmeijer^*, H. B. Van Der Worp, G. J. Amelink, A. Algra, J. Van Gijn, L. J. Kappelle

^*Corresponding author for this work

Research output: Contribution to journal › Review article › Academic › peer-review

5 Citations (Scopus)

Abstract

Patients with a hemispheric infarct and massive space-occupying brain oedema have a poor prognosis. Despite intensive conservative treatment, the case fatality rate may be as high as 80%, and most survivors are left severely disabled. Non-randomised studies suggest that decompressive surgery substantially reduces mortality and improves the functional outcome of survivors. The 'Hemicraniectomy after middle cerebral artery infarction with life-threatening edema trial' (HAMLET) is a newly-conceived randomised multi-centre clinical trial that compares the efficacy of decompressive surgery to improve functional outcome with that of conservative treatment in patients with space-occupying supratentorial infarction.

Translated title of the contribution	Surgical decompression in space-occupying cerebral infarct; notification of a randomised trial
Original language	Dutch
Pages (from-to)	2594-2596
Number of pages	3
Journal	Nederlands tijdschrift voor geneeskunde
Volume	147
Issue number	52
Publication status	Published - 27 Dec 2003
Externally published	Yes

Keywords

n/a OA procedure

Cite this

@article{f8d1121ca3704cf5bf54ab4241ec0242,

title = "Chirurgische decompressie bij het ruimte-innemende herseninfarct; aanmelding voor een gerandomiseerde trial",

abstract = "Patients with a hemispheric infarct and massive space-occupying brain oedema have a poor prognosis. Despite intensive conservative treatment, the case fatality rate may be as high as 80%, and most survivors are left severely disabled. Non-randomised studies suggest that decompressive surgery substantially reduces mortality and improves the functional outcome of survivors. The 'Hemicraniectomy after middle cerebral artery infarction with life-threatening edema trial' (HAMLET) is a newly-conceived randomised multi-centre clinical trial that compares the efficacy of decompressive surgery to improve functional outcome with that of conservative treatment in patients with space-occupying supratentorial infarction.",

keywords = "n/a OA procedure",

author = "J. Hofmeijer and {Van Der Worp}, {H. B.} and Amelink, {G. J.} and A. Algra and {Van Gijn}, J. and Kappelle, {L. J.}",

year = "2003",

month = dec,

day = "27",

language = "Dutch",

volume = "147",

pages = "2594--2596",

journal = "Nederlands tijdschrift voor geneeskunde",

issn = "0028-2162",

publisher = "Bohn Stafleu Van Loghum",

number = "52",

}

TY - JOUR

T1 - Chirurgische decompressie bij het ruimte-innemende herseninfarct; aanmelding voor een gerandomiseerde trial

AU - Hofmeijer, J.

AU - Van Der Worp, H. B.

AU - Amelink, G. J.

AU - Algra, A.

AU - Van Gijn, J.

AU - Kappelle, L. J.

PY - 2003/12/27

Y1 - 2003/12/27

N2 - Patients with a hemispheric infarct and massive space-occupying brain oedema have a poor prognosis. Despite intensive conservative treatment, the case fatality rate may be as high as 80%, and most survivors are left severely disabled. Non-randomised studies suggest that decompressive surgery substantially reduces mortality and improves the functional outcome of survivors. The 'Hemicraniectomy after middle cerebral artery infarction with life-threatening edema trial' (HAMLET) is a newly-conceived randomised multi-centre clinical trial that compares the efficacy of decompressive surgery to improve functional outcome with that of conservative treatment in patients with space-occupying supratentorial infarction.

AB - Patients with a hemispheric infarct and massive space-occupying brain oedema have a poor prognosis. Despite intensive conservative treatment, the case fatality rate may be as high as 80%, and most survivors are left severely disabled. Non-randomised studies suggest that decompressive surgery substantially reduces mortality and improves the functional outcome of survivors. The 'Hemicraniectomy after middle cerebral artery infarction with life-threatening edema trial' (HAMLET) is a newly-conceived randomised multi-centre clinical trial that compares the efficacy of decompressive surgery to improve functional outcome with that of conservative treatment in patients with space-occupying supratentorial infarction.

KW - n/a OA procedure

UR - http://www.scopus.com/inward/record.url?scp=0347755064&partnerID=8YFLogxK

M3 - Review article

C2 - 14723030

AN - SCOPUS:0347755064

SN - 0028-2162

VL - 147

SP - 2594

EP - 2596

JO - Nederlands tijdschrift voor geneeskunde

JF - Nederlands tijdschrift voor geneeskunde

IS - 52

ER -

Chirurgische decompressie bij het ruimte-innemende herseninfarct; aanmelding voor een gerandomiseerde trial

Abstract

Keywords

Other files and links

Fingerprint

Cite this