Chirurgische decompressie bij het ruimte-innemende herseninfarct; aanmelding voor een gerandomiseerde trial

Translated title of the contribution: Surgical decompression in space-occupying cerebral infarct; notification of a randomised trial

J. Hofmeijer*, H. B. Van Der Worp, G. J. Amelink, A. Algra, J. Van Gijn, L. J. Kappelle

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

5 Citations (Scopus)

Abstract

Patients with a hemispheric infarct and massive space-occupying brain oedema have a poor prognosis. Despite intensive conservative treatment, the case fatality rate may be as high as 80%, and most survivors are left severely disabled. Non-randomised studies suggest that decompressive surgery substantially reduces mortality and improves the functional outcome of survivors. The 'Hemicraniectomy after middle cerebral artery infarction with life-threatening edema trial' (HAMLET) is a newly-conceived randomised multi-centre clinical trial that compares the efficacy of decompressive surgery to improve functional outcome with that of conservative treatment in patients with space-occupying supratentorial infarction.

Translated title of the contributionSurgical decompression in space-occupying cerebral infarct; notification of a randomised trial
Original languageDutch
Pages (from-to)2594-2596
Number of pages3
JournalNederlands tijdschrift voor geneeskunde
Volume147
Issue number52
Publication statusPublished - 27 Dec 2003
Externally publishedYes

Keywords

  • n/a OA procedure

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