Classifying post-stroke shoulder pain: Can the DN4 be helpful?

Meyke Roosink, Robert T.M. van Dongen, Gerbert J. Renzenbrink, Maarten Joost IJzerman

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

Abstract

The etiology of post-stroke shoulder pain (PSSP) is largely unclear and may involve both nociceptive and neuropathic mechanisms. No gold standard is present for PSSP diagnosis. The neuropathic pain diagnostic questionnaire (DN4), was originally developed to identify neuropathic pain in the clinical context. In this study we used the DN4 to categorize PSSP patients and compared symptoms and signs suggestive of either nociceptive or neuropathic pain. Pain complaints and sensory functions were compared between patients with chronic PSSP scoring at least four (DN4+, n = 9) or less than four (DN4-, n = 10) on the DN4. Pain was assessed using a numeric rating scale and the McGill pain questionnaire. Sensory functions were assessed using clinical examination and quantitative sensory testing combined with a cold pressor test. Patients classified as DN4+ reported constant pain, higher pain intensity, a higher impact of pain on daily living, more frequent loss of cold sensation, reduced QST thresholds at the unaffected side and increased QST thresholds at the affected side. Notably, several symptoms and signs suggestive of either neuropathic or nociceptive pain corresponded to the subgroups DN4+ and DN4- respectively. However, since the pathophysiological mechanisms remain unclear and none of the sensory signs could be exclusively related to either DN4+ or DN4-, PSSP prognosis and treatment should not be solely based on the DN4. Nonetheless, a thorough assessment of neuropathic and nociceptive pain complaints and somatosensory functions should be included in the diagnostic work-up of PSSP.
Original languageEnglish
Pages (from-to)99-102
Number of pages4
JournalEuropean journal of pain
Volume15
Issue number1
DOIs
Publication statusPublished - 9 Jan 2012

Fingerprint

Shoulder Pain
Neuralgia
Stroke
Nociceptive Pain
Pain
Signs and Symptoms
Hypesthesia
Pain Measurement

Keywords

  • Shoulder pain
  • Neuropathic pain diagnostic questionnaire
  • METIS-271419
  • Stroke
  • EWI-18778
  • IR-75501
  • Quantitative sensory testing

Cite this

Roosink, Meyke ; van Dongen, Robert T.M. ; Renzenbrink, Gerbert J. ; IJzerman, Maarten Joost. / Classifying post-stroke shoulder pain : Can the DN4 be helpful?. In: European journal of pain. 2012 ; Vol. 15, No. 1. pp. 99-102.
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Classifying post-stroke shoulder pain : Can the DN4 be helpful? / Roosink, Meyke; van Dongen, Robert T.M.; Renzenbrink, Gerbert J.; IJzerman, Maarten Joost.

In: European journal of pain, Vol. 15, No. 1, 09.01.2012, p. 99-102.

Research output: Contribution to journalArticleAcademicpeer-review

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T2 - Can the DN4 be helpful?

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N2 - The etiology of post-stroke shoulder pain (PSSP) is largely unclear and may involve both nociceptive and neuropathic mechanisms. No gold standard is present for PSSP diagnosis. The neuropathic pain diagnostic questionnaire (DN4), was originally developed to identify neuropathic pain in the clinical context. In this study we used the DN4 to categorize PSSP patients and compared symptoms and signs suggestive of either nociceptive or neuropathic pain. Pain complaints and sensory functions were compared between patients with chronic PSSP scoring at least four (DN4+, n = 9) or less than four (DN4-, n = 10) on the DN4. Pain was assessed using a numeric rating scale and the McGill pain questionnaire. Sensory functions were assessed using clinical examination and quantitative sensory testing combined with a cold pressor test. Patients classified as DN4+ reported constant pain, higher pain intensity, a higher impact of pain on daily living, more frequent loss of cold sensation, reduced QST thresholds at the unaffected side and increased QST thresholds at the affected side. Notably, several symptoms and signs suggestive of either neuropathic or nociceptive pain corresponded to the subgroups DN4+ and DN4- respectively. However, since the pathophysiological mechanisms remain unclear and none of the sensory signs could be exclusively related to either DN4+ or DN4-, PSSP prognosis and treatment should not be solely based on the DN4. Nonetheless, a thorough assessment of neuropathic and nociceptive pain complaints and somatosensory functions should be included in the diagnostic work-up of PSSP.

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KW - IR-75501

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