Clinical assessment of drug-eluting stents: Twente trial and beyond

Kenneth Tandjung

doi:10.3990/1.9789036536660

Clinical assessment of drug-eluting stents: Twente trial and beyond

Kenneth Tandjung

Faculty of Behavioural, Management and Social Sciences

Research output: Thesis › PhD Thesis - Research external, graduation UT

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Abstract

Stents have revolutionized the treatment of obstructive coronary disease by improving the safety of percutaneous coronary intervention (PCI) and reducing the need for repeat revascularization. First-generation drug-eluting stents (DES) were highly efficacious, as they further reduced the need for reintervention, but they left room for improvement in safety and stent deliverability. Newer-generation DES were designed for better biocompatibility and deliverability. Nevertheless, only few clinical data on the safety and efficacy of these newer-generation DES are available. This thesis has investigated various aspects of both safety and efficacy of newer-generation DES.

Original language	English
Awarding Institution	University of Twente
Supervisors/Advisors	von Birgelen, Clemens, Supervisor
Award date	25 Jun 2014
Place of Publication	Enschede
Publisher	University of Twente
Print ISBNs	978-90-365-3666-0
DOIs	https://doi.org/10.3990/1.9789036536660
Publication status	Published - 25 Jun 2014

Keywords

METIS-303875
IR-91283

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Cite this

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title = "Clinical assessment of drug-eluting stents: Twente trial and beyond",

abstract = "Stents have revolutionized the treatment of obstructive coronary disease by improving the safety of percutaneous coronary intervention (PCI) and reducing the need for repeat revascularization. First-generation drug-eluting stents (DES) were highly efficacious, as they further reduced the need for reintervention, but they left room for improvement in safety and stent deliverability. Newer-generation DES were designed for better biocompatibility and deliverability. Nevertheless, only few clinical data on the safety and efficacy of these newer-generation DES are available. This thesis has investigated various aspects of both safety and efficacy of newer-generation DES.",

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N2 - Stents have revolutionized the treatment of obstructive coronary disease by improving the safety of percutaneous coronary intervention (PCI) and reducing the need for repeat revascularization. First-generation drug-eluting stents (DES) were highly efficacious, as they further reduced the need for reintervention, but they left room for improvement in safety and stent deliverability. Newer-generation DES were designed for better biocompatibility and deliverability. Nevertheless, only few clinical data on the safety and efficacy of these newer-generation DES are available. This thesis has investigated various aspects of both safety and efficacy of newer-generation DES.

AB - Stents have revolutionized the treatment of obstructive coronary disease by improving the safety of percutaneous coronary intervention (PCI) and reducing the need for repeat revascularization. First-generation drug-eluting stents (DES) were highly efficacious, as they further reduced the need for reintervention, but they left room for improvement in safety and stent deliverability. Newer-generation DES were designed for better biocompatibility and deliverability. Nevertheless, only few clinical data on the safety and efficacy of these newer-generation DES are available. This thesis has investigated various aspects of both safety and efficacy of newer-generation DES.

KW - METIS-303875

KW - IR-91283

U2 - 10.3990/1.9789036536660

DO - 10.3990/1.9789036536660

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SN - 978-90-365-3666-0

PB - University of Twente

CY - Enschede

ER -

Clinical assessment of drug-eluting stents: Twente trial and beyond

Abstract

Keywords

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