Clinical Relevance of Immersive Virtual Reality in the Assessment and Treatment of Addictive Disorders: A Systematic Review and Future Perspective

Simon Langener; Joanne VanDerNagel; Jeannette van Manen; Wiebren Markus; Boukje Dijkstra; Laura DeFuentes-Merillas; Randy Klaassen; Janika Heitmann; Dirk Heylen; Arnt Schellekens

doi:10.3390/jcm10163658

Clinical Relevance of Immersive Virtual Reality in the Assessment and Treatment of Addictive Disorders: A Systematic Review and Future Perspective

Simon Langener^*, Joanne VanDerNagel, Jeannette van Manen, Wiebren Markus, Boukje Dijkstra, Laura DeFuentes-Merillas, Randy Klaassen, Janika Heitmann, Dirk Heylen, Arnt Schellekens

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Background: Virtual reality (VR) has been investigated in a variety of psychiatric disorders, including addictive disorders (ADs)

Objective: This systematic review evaluates the current evidence of immersive VR (using head-mounted displays) in the clinical assessment and treatment of ADs;

Method: PubMed and PsycINFO were queried for publications up to November 2020

Results: We screened 4519 titles, 114 abstracts and 85 full-texts, and analyzed 36 articles regarding the clinical assessment (i.e., diagnostic and prognostic value; n = 19) and treatment (i.e., interventions; n = 17) of ADs. Though most VR assessment studies (n = 15/19) showed associations between VR-induced cue-reactivity and clinical parameters, only two studies specified diagnostic value. VR treatment studies based on exposure therapy showed no or negative effects. However, other VR interventions like embodied and aversive learning paradigms demonstrated positive findings. The overall study quality was rather poor

Conclusion: Though VR in ADs provides ecologically valid environments to induce cue-reactivity and provide new treatment paradigms, the added clinical value in assessment and therapy remains to be elucidated before VR can be applied in clinical care. Therefore, future work should investigate VR efficacy in randomized clinical trials using well-defined clinical endpoints

Original language	English
Article number	3658
Journal	Journal of Clinical Medicine
Volume	10
Issue number	16
DOIs	https://doi.org/10.3390/jcm10163658
Publication status	Published - 18 Aug 2021

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UT-Gold-D

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Langener, S., VanDerNagel, J., Manen, J. V., Markus, W., Dijkstra, B., DeFuentes-Merillas, L., Klaassen, R., Heitmann, J., Heylen, D., & Schellekens, A. (2021). Clinical Relevance of Immersive Virtual Reality in the Assessment and Treatment of Addictive Disorders: A Systematic Review and Future Perspective. Journal of Clinical Medicine, 10(16), Article 3658. https://doi.org/10.3390/jcm10163658

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abstract = "Background: Virtual reality (VR) has been investigated in a variety of psychiatric disorders, including addictive disorders (ADs)Objective: This systematic review evaluates the current evidence of immersive VR (using head-mounted displays) in the clinical assessment and treatment of ADs;Method: PubMed and PsycINFO were queried for publications up to November 2020Results: We screened 4519 titles, 114 abstracts and 85 full-texts, and analyzed 36 articles regarding the clinical assessment (i.e., diagnostic and prognostic value; n = 19) and treatment (i.e., interventions; n = 17) of ADs. Though most VR assessment studies (n = 15/19) showed associations between VR-induced cue-reactivity and clinical parameters, only two studies specified diagnostic value. VR treatment studies based on exposure therapy showed no or negative effects. However, other VR interventions like embodied and aversive learning paradigms demonstrated positive findings. The overall study quality was rather poorConclusion: Though VR in ADs provides ecologically valid environments to induce cue-reactivity and provide new treatment paradigms, the added clinical value in assessment and therapy remains to be elucidated before VR can be applied in clinical care. Therefore, future work should investigate VR efficacy in randomized clinical trials using well-defined clinical endpoints",

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author = "Simon Langener and Joanne VanDerNagel and Manen, {Jeannette van} and Wiebren Markus and Boukje Dijkstra and Laura DeFuentes-Merillas and Randy Klaassen and Janika Heitmann and Dirk Heylen and Arnt Schellekens",

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Langener, S , VanDerNagel, J, Manen, JV, Markus, W, Dijkstra, B, DeFuentes-Merillas, L, Klaassen, R, Heitmann, J, Heylen, D & Schellekens, A 2021, 'Clinical Relevance of Immersive Virtual Reality in the Assessment and Treatment of Addictive Disorders: A Systematic Review and Future Perspective', Journal of Clinical Medicine, vol. 10, no. 16, 3658. https://doi.org/10.3390/jcm10163658

TY - JOUR

T1 - Clinical Relevance of Immersive Virtual Reality in the Assessment and Treatment of Addictive Disorders

T2 - A Systematic Review and Future Perspective

AU - Langener, Simon

AU - VanDerNagel, Joanne

AU - Manen, Jeannette van

AU - Markus, Wiebren

AU - Dijkstra, Boukje

AU - DeFuentes-Merillas, Laura

AU - Klaassen, Randy

AU - Heitmann, Janika

AU - Heylen, Dirk

AU - Schellekens, Arnt

PY - 2021/8/18

Y1 - 2021/8/18

N2 - Background: Virtual reality (VR) has been investigated in a variety of psychiatric disorders, including addictive disorders (ADs)Objective: This systematic review evaluates the current evidence of immersive VR (using head-mounted displays) in the clinical assessment and treatment of ADs;Method: PubMed and PsycINFO were queried for publications up to November 2020Results: We screened 4519 titles, 114 abstracts and 85 full-texts, and analyzed 36 articles regarding the clinical assessment (i.e., diagnostic and prognostic value; n = 19) and treatment (i.e., interventions; n = 17) of ADs. Though most VR assessment studies (n = 15/19) showed associations between VR-induced cue-reactivity and clinical parameters, only two studies specified diagnostic value. VR treatment studies based on exposure therapy showed no or negative effects. However, other VR interventions like embodied and aversive learning paradigms demonstrated positive findings. The overall study quality was rather poorConclusion: Though VR in ADs provides ecologically valid environments to induce cue-reactivity and provide new treatment paradigms, the added clinical value in assessment and therapy remains to be elucidated before VR can be applied in clinical care. Therefore, future work should investigate VR efficacy in randomized clinical trials using well-defined clinical endpoints

AB - Background: Virtual reality (VR) has been investigated in a variety of psychiatric disorders, including addictive disorders (ADs)Objective: This systematic review evaluates the current evidence of immersive VR (using head-mounted displays) in the clinical assessment and treatment of ADs;Method: PubMed and PsycINFO were queried for publications up to November 2020Results: We screened 4519 titles, 114 abstracts and 85 full-texts, and analyzed 36 articles regarding the clinical assessment (i.e., diagnostic and prognostic value; n = 19) and treatment (i.e., interventions; n = 17) of ADs. Though most VR assessment studies (n = 15/19) showed associations between VR-induced cue-reactivity and clinical parameters, only two studies specified diagnostic value. VR treatment studies based on exposure therapy showed no or negative effects. However, other VR interventions like embodied and aversive learning paradigms demonstrated positive findings. The overall study quality was rather poorConclusion: Though VR in ADs provides ecologically valid environments to induce cue-reactivity and provide new treatment paradigms, the added clinical value in assessment and therapy remains to be elucidated before VR can be applied in clinical care. Therefore, future work should investigate VR efficacy in randomized clinical trials using well-defined clinical endpoints

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DO - 10.3390/jcm10163658

M3 - Article

SN - 2077-0383

VL - 10

JO - Journal of Clinical Medicine

JF - Journal of Clinical Medicine

IS - 16

M1 - 3658

ER -

Clinical Relevance of Immersive Virtual Reality in the Assessment and Treatment of Addictive Disorders: A Systematic Review and Future Perspective

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