Closed loop physiological ECMO control

Marian Walter*, C. Brendle, R. Bensberg, R. Kopp, J. Arens, A. Stollenwerk, S. Leonhardt

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

8 Citations (Scopus)


Patients suffering acute lung failure depend on artificial ventilation in order to survive. In severe cases, this therapy may not be sufficient any more and long term extracorporeal membrane oxygenation (ECMO) may be used as a last chance rescue therapy. Adapted from short term cardiopulmonary bypass, these machines now need an increased ability for autonomous and unsupervised operation. Apart from the material aspects (hemolysis and long term biocompatibility), a prerequisite for safe and reliable operation is the implementation of an adequate automation and safety scheme. Extending previous work [1,2] where we focused on machine internal control and the modeling of the biological process, this paper presents an integrated control of the physiological target values.

Original languageEnglish
Title of host publication5th European Conference of the International Federation for Medical and Biological Engineering 14–18 September 2011, Budapest, Hungary
EditorsAkos Jobbagy
Number of pages4
ISBN (Electronic)978-3-642-23508-5
Publication statusPublished - 9 Nov 2011
Externally publishedYes

Publication series

NameIFMBE proceedings
ISSN (Print)1680-0737


  • automatic control
  • ECMO
  • membrane oxygenation


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