Collagen-based scaffolds for tissue engineering of small-diameter blood vessels

Laura Buttafoco

Research output: ThesisPhD Thesis - Research UT, graduation UT

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Atherosclerotic vascular disease, including peripheral and coronary artery disease, is the main cause of morbidity and mortality in the Western society. Although synthetic blood vessel prostheses are successfully being used for large-diameter vascular reconstructions, until now no functional small-diameter (< 6 mm) artificial vascular graft is available. Autologous veins and arteries are currently being used as vessel substitutes, but limitations in arteries supply and compliance mismatch are some of their main drawbacks encountered in this approach. Therefore, tissue engineering of small-diameter vascular grafts is an expanding area of research.
Original languageEnglish
Awarding Institution
  • University of Twente
  • Feijen, J., Supervisor
  • Vermes, I., Supervisor
  • Poot, A.A., Co-Supervisor
Award date18 Feb 2005
Place of PublicationEnschede
Print ISBNs90-365-2135-1
Publication statusPublished - 18 Feb 2005


  • METIS-224368
  • IR-48256


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