Combined Lab-on-a-Chip and microarray approach for biomolecular interaction sensing using surface plasmon resonance imaging

G. Krishnamoorthy, G. Krishnamoorthy, J.B. Beusink, J.B. Beusink, Edwin Carlen, Stefan Schlautmann, Hans L. de Boer, Albert van den Berg, Richardus B.M. Schasfoort

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

29 Citations (Scopus)
24 Downloads (Pure)

Abstract

Surface plasmon resonance imaging (SPR) is a well-established label-free detection technique for real-time biomolecular interaction measurements. An integrated LOC sensing system with fluidic control for sample movement to specific locations on microarray surface in combination with SPR imaging is demonstrated by the measurements of human IgG and anti-IgG interactions from 24 patterned regions.
Original languageUndefined
Title of host publicationEleventh International Conference on Miniaturized Systems for Chemistry and Life Sciences - The proceedings of microTAS 2007 Conference
EditorsJ.L. Viovy, P Tabeling, S. Descroix, L. Malaquin
Place of PublicationSan Diego
PublisherChemical and Biological Micro Systems Society
Pages676-678
Number of pages3
ISBN (Print)978-0-9798064-0-7
Publication statusPublished - 7 Oct 2007
Event11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2007 - Paris, France
Duration: 7 Oct 200711 Oct 2007
Conference number: 11

Publication series

NameMicro Total Analysis Systems
PublisherChemical and Biological Microsystems society
NumberPaper P-NS
Volume1
ISSN (Print)1556-5890

Conference

Conference11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2007
Abbreviated titleMicroTAS
CountryFrance
CityParis
Period7/10/0711/10/07

Keywords

  • IR-64439
  • Biomolecular Interaction
  • SPR
  • METIS-245753
  • Lab on a chip
  • EWI-11330
  • Micro-array

Cite this

Krishnamoorthy, G., Krishnamoorthy, G., Beusink, J. B., Beusink, J. B., Carlen, E., Schlautmann, S., ... Schasfoort, R. B. M. (2007). Combined Lab-on-a-Chip and microarray approach for biomolecular interaction sensing using surface plasmon resonance imaging. In J. L. Viovy, P. Tabeling, S. Descroix, & L. Malaquin (Eds.), Eleventh International Conference on Miniaturized Systems for Chemistry and Life Sciences - The proceedings of microTAS 2007 Conference (pp. 676-678). (Micro Total Analysis Systems; Vol. 1, No. Paper P-NS). San Diego: Chemical and Biological Micro Systems Society.
Krishnamoorthy, G. ; Krishnamoorthy, G. ; Beusink, J.B. ; Beusink, J.B. ; Carlen, Edwin ; Schlautmann, Stefan ; de Boer, Hans L. ; van den Berg, Albert ; Schasfoort, Richardus B.M. / Combined Lab-on-a-Chip and microarray approach for biomolecular interaction sensing using surface plasmon resonance imaging. Eleventh International Conference on Miniaturized Systems for Chemistry and Life Sciences - The proceedings of microTAS 2007 Conference. editor / J.L. Viovy ; P Tabeling ; S. Descroix ; L. Malaquin. San Diego : Chemical and Biological Micro Systems Society, 2007. pp. 676-678 (Micro Total Analysis Systems; Paper P-NS).
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abstract = "Surface plasmon resonance imaging (SPR) is a well-established label-free detection technique for real-time biomolecular interaction measurements. An integrated LOC sensing system with fluidic control for sample movement to specific locations on microarray surface in combination with SPR imaging is demonstrated by the measurements of human IgG and anti-IgG interactions from 24 patterned regions.",
keywords = "IR-64439, Biomolecular Interaction, SPR, METIS-245753, Lab on a chip, EWI-11330, Micro-array",
author = "G. Krishnamoorthy and G. Krishnamoorthy and J.B. Beusink and J.B. Beusink and Edwin Carlen and Stefan Schlautmann and {de Boer}, {Hans L.} and {van den Berg}, Albert and Schasfoort, {Richardus B.M.}",
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month = "10",
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isbn = "978-0-9798064-0-7",
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Krishnamoorthy, G, Krishnamoorthy, G, Beusink, JB, Beusink, JB, Carlen, E, Schlautmann, S, de Boer, HL, van den Berg, A & Schasfoort, RBM 2007, Combined Lab-on-a-Chip and microarray approach for biomolecular interaction sensing using surface plasmon resonance imaging. in JL Viovy, P Tabeling, S Descroix & L Malaquin (eds), Eleventh International Conference on Miniaturized Systems for Chemistry and Life Sciences - The proceedings of microTAS 2007 Conference. Micro Total Analysis Systems, no. Paper P-NS, vol. 1, Chemical and Biological Micro Systems Society, San Diego, pp. 676-678, 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2007, Paris, France, 7/10/07.

Combined Lab-on-a-Chip and microarray approach for biomolecular interaction sensing using surface plasmon resonance imaging. / Krishnamoorthy, G.; Krishnamoorthy, G.; Beusink, J.B.; Beusink, J.B.; Carlen, Edwin; Schlautmann, Stefan; de Boer, Hans L.; van den Berg, Albert; Schasfoort, Richardus B.M.

Eleventh International Conference on Miniaturized Systems for Chemistry and Life Sciences - The proceedings of microTAS 2007 Conference. ed. / J.L. Viovy; P Tabeling; S. Descroix; L. Malaquin. San Diego : Chemical and Biological Micro Systems Society, 2007. p. 676-678 (Micro Total Analysis Systems; Vol. 1, No. Paper P-NS).

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

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AU - Carlen, Edwin

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AU - van den Berg, Albert

AU - Schasfoort, Richardus B.M.

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N2 - Surface plasmon resonance imaging (SPR) is a well-established label-free detection technique for real-time biomolecular interaction measurements. An integrated LOC sensing system with fluidic control for sample movement to specific locations on microarray surface in combination with SPR imaging is demonstrated by the measurements of human IgG and anti-IgG interactions from 24 patterned regions.

AB - Surface plasmon resonance imaging (SPR) is a well-established label-free detection technique for real-time biomolecular interaction measurements. An integrated LOC sensing system with fluidic control for sample movement to specific locations on microarray surface in combination with SPR imaging is demonstrated by the measurements of human IgG and anti-IgG interactions from 24 patterned regions.

KW - IR-64439

KW - Biomolecular Interaction

KW - SPR

KW - METIS-245753

KW - Lab on a chip

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KW - Micro-array

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BT - Eleventh International Conference on Miniaturized Systems for Chemistry and Life Sciences - The proceedings of microTAS 2007 Conference

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PB - Chemical and Biological Micro Systems Society

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Krishnamoorthy G, Krishnamoorthy G, Beusink JB, Beusink JB, Carlen E, Schlautmann S et al. Combined Lab-on-a-Chip and microarray approach for biomolecular interaction sensing using surface plasmon resonance imaging. In Viovy JL, Tabeling P, Descroix S, Malaquin L, editors, Eleventh International Conference on Miniaturized Systems for Chemistry and Life Sciences - The proceedings of microTAS 2007 Conference. San Diego: Chemical and Biological Micro Systems Society. 2007. p. 676-678. (Micro Total Analysis Systems; Paper P-NS).