Combined Lab-on-a-Chip and microarray approach for biomolecular interaction sensing using surface plasmon resonance imaging

G. Krishnamoorthy; J.B. Beusink; Edwin Carlen; Stefan Schlautmann; Hans L. de Boer; Albert van den Berg; Richardus B.M. Schasfoort

Combined Lab-on-a-Chip and microarray approach for biomolecular interaction sensing using surface plasmon resonance imaging

G. Krishnamoorthy, J.B. Beusink, Edwin Carlen, Stefan Schlautmann, Hans L. de Boer, Albert van den Berg, Richardus B.M. Schasfoort

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

29 Citations (Scopus)

33 Downloads (Pure)

Abstract

Surface plasmon resonance imaging (SPR) is a well-established label-free detection technique for real-time biomolecular interaction measurements. An integrated LOC sensing system with fluidic control for sample movement to specific locations on microarray surface in combination with SPR imaging is demonstrated by the measurements of human IgG and anti-IgG interactions from 24 patterned regions.

Original language	English
Title of host publication	Eleventh International Conference on Miniaturized Systems for Chemistry and Life Sciences - The proceedings of microTAS 2007 Conference
Editors	J.L. Viovy, P Tabeling, S. Descroix, L. Malaquin
Place of Publication	San Diego
Publisher	Chemical and Biological Micro Systems Society
Pages	676-678
Number of pages	3
ISBN (Print)	978-0-9798064-0-7
Publication status	Published - 7 Oct 2007
Event	11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2007 - Paris, France Duration: 7 Oct 2007 → 11 Oct 2007 Conference number: 11

Publication series

Name	Micro Total Analysis Systems
Publisher	Chemical and Biological Microsystems society
Number	Paper P-NS
Volume	1
ISSN (Print)	1556-5890

Conference

Conference	11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2007
Abbreviated title	MicroTAS
Country	France
City	Paris
Period	7/10/07 → 11/10/07

Keywords

IR-64439
Biomolecular Interaction
SPR
METIS-245753
Lab on a chip
EWI-11330
Micro-array

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Krishnamoorthy, G., Beusink, J. B., Carlen, E., Schlautmann, S., de Boer, H. L., van den Berg, A., & Schasfoort, R. B. M. (2007). Combined Lab-on-a-Chip and microarray approach for biomolecular interaction sensing using surface plasmon resonance imaging. In J. L. Viovy, P. Tabeling, S. Descroix, & L. Malaquin (Eds.), Eleventh International Conference on Miniaturized Systems for Chemistry and Life Sciences - The proceedings of microTAS 2007 Conference (pp. 676-678). (Micro Total Analysis Systems; Vol. 1, No. Paper P-NS). Chemical and Biological Micro Systems Society.

Krishnamoorthy, G. ; Beusink, J.B. ; Carlen, Edwin ; Schlautmann, Stefan ; de Boer, Hans L. ; van den Berg, Albert ; Schasfoort, Richardus B.M. / Combined Lab-on-a-Chip and microarray approach for biomolecular interaction sensing using surface plasmon resonance imaging. Eleventh International Conference on Miniaturized Systems for Chemistry and Life Sciences - The proceedings of microTAS 2007 Conference. editor / J.L. Viovy ; P Tabeling ; S. Descroix ; L. Malaquin. San Diego : Chemical and Biological Micro Systems Society, 2007. pp. 676-678 (Micro Total Analysis Systems; Paper P-NS).

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title = "Combined Lab-on-a-Chip and microarray approach for biomolecular interaction sensing using surface plasmon resonance imaging",

abstract = "Surface plasmon resonance imaging (SPR) is a well-established label-free detection technique for real-time biomolecular interaction measurements. An integrated LOC sensing system with fluidic control for sample movement to specific locations on microarray surface in combination with SPR imaging is demonstrated by the measurements of human IgG and anti-IgG interactions from 24 patterned regions.",

keywords = "IR-64439, Biomolecular Interaction, SPR, METIS-245753, Lab on a chip, EWI-11330, Micro-array",

author = "G. Krishnamoorthy and J.B. Beusink and Edwin Carlen and Stefan Schlautmann and {de Boer}, {Hans L.} and {van den Berg}, Albert and Schasfoort, {Richardus B.M.}",

year = "2007",

month = oct,

day = "7",

language = "English",

isbn = "978-0-9798064-0-7",

series = "Micro Total Analysis Systems",

publisher = "Chemical and Biological Micro Systems Society",

number = "Paper P-NS",

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editor = "J.L. Viovy and P Tabeling and S. Descroix and L. Malaquin",

booktitle = "Eleventh International Conference on Miniaturized Systems for Chemistry and Life Sciences - The proceedings of microTAS 2007 Conference",

note = "11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2007, MicroTAS ; Conference date: 07-10-2007 Through 11-10-2007",

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Krishnamoorthy, G, Beusink, JB, Carlen, E, Schlautmann, S , de Boer, HL , van den Berg, A & Schasfoort, RBM 2007, Combined Lab-on-a-Chip and microarray approach for biomolecular interaction sensing using surface plasmon resonance imaging. in JL Viovy, P Tabeling, S Descroix & L Malaquin (eds), Eleventh International Conference on Miniaturized Systems for Chemistry and Life Sciences - The proceedings of microTAS 2007 Conference. Micro Total Analysis Systems, no. Paper P-NS, vol. 1, Chemical and Biological Micro Systems Society, San Diego, pp. 676-678, 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2007, Paris, France, 7/10/07.

Combined Lab-on-a-Chip and microarray approach for biomolecular interaction sensing using surface plasmon resonance imaging. / Krishnamoorthy, G.; Beusink, J.B.; Carlen, Edwin; Schlautmann, Stefan ; de Boer, Hans L.; van den Berg, Albert ; Schasfoort, Richardus B.M.

Eleventh International Conference on Miniaturized Systems for Chemistry and Life Sciences - The proceedings of microTAS 2007 Conference. ed. / J.L. Viovy; P Tabeling; S. Descroix; L. Malaquin. San Diego : Chemical and Biological Micro Systems Society, 2007. p. 676-678 (Micro Total Analysis Systems; Vol. 1, No. Paper P-NS).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

TY - GEN

T1 - Combined Lab-on-a-Chip and microarray approach for biomolecular interaction sensing using surface plasmon resonance imaging

AU - Krishnamoorthy, G.

AU - Beusink, J.B.

AU - Carlen, Edwin

AU - Schlautmann, Stefan

AU - de Boer, Hans L.

AU - van den Berg, Albert

AU - Schasfoort, Richardus B.M.

N1 - Conference code: 11

PY - 2007/10/7

Y1 - 2007/10/7

N2 - Surface plasmon resonance imaging (SPR) is a well-established label-free detection technique for real-time biomolecular interaction measurements. An integrated LOC sensing system with fluidic control for sample movement to specific locations on microarray surface in combination with SPR imaging is demonstrated by the measurements of human IgG and anti-IgG interactions from 24 patterned regions.

AB - Surface plasmon resonance imaging (SPR) is a well-established label-free detection technique for real-time biomolecular interaction measurements. An integrated LOC sensing system with fluidic control for sample movement to specific locations on microarray surface in combination with SPR imaging is demonstrated by the measurements of human IgG and anti-IgG interactions from 24 patterned regions.

KW - IR-64439

KW - Biomolecular Interaction

KW - SPR

KW - METIS-245753

KW - Lab on a chip

KW - EWI-11330

KW - Micro-array

M3 - Conference contribution

SN - 978-0-9798064-0-7

T3 - Micro Total Analysis Systems

SP - 676

EP - 678

BT - Eleventh International Conference on Miniaturized Systems for Chemistry and Life Sciences - The proceedings of microTAS 2007 Conference

A2 - Viovy, J.L.

A2 - Tabeling, P

A2 - Descroix, S.

A2 - Malaquin, L.

PB - Chemical and Biological Micro Systems Society

CY - San Diego

T2 - 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2007

Y2 - 7 October 2007 through 11 October 2007

ER -

Krishnamoorthy G, Beusink JB, Carlen E, Schlautmann S , de Boer HL , van den Berg A et al. Combined Lab-on-a-Chip and microarray approach for biomolecular interaction sensing using surface plasmon resonance imaging. In Viovy JL, Tabeling P, Descroix S, Malaquin L, editors, Eleventh International Conference on Miniaturized Systems for Chemistry and Life Sciences - The proceedings of microTAS 2007 Conference. San Diego: Chemical and Biological Micro Systems Society. 2007. p. 676-678. (Micro Total Analysis Systems; Paper P-NS).