Comparison of outcome in stroke patients admitted during working hours vs. off-hours; a single-center cohort study

M. P. Tuinman (Corresponding Author), E. G.A. van Golde, R. P. Portier, I. L.H. Knottnerus, J. van der Palen, H. M. den Hertog, P. J.A.M. Brouwers

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Abstract

INTRODUCTION We aimed to disprove an in-hospital off-hour effect in stroke patients by adjusting for disease severity and poor prognostic findings on imaging. PATIENTS AND METHODS Our study included 5378 patients from a single center prospective stroke registry of a large teaching hospital in the Netherlands, admitted between January 2003 and June 2015. Patients were categorized by admission time, off-hours (OH) or working hours (WH). The in-hospital mortality, 7-day mortality, unfavorable functional outcome (modified Rankin scale > 2) and discharge to home were analyzed. Results were adjusted for age, sex, stroke severity (NIHSS score) and unfavorable findings on imaging of the brain (midline shift and dense vessel sign). RESULTS Overall, 2796 patients (52%) were admitted during OH, which had a higher NIHSS score [3 (IQR 2-8) vs. 3 (IQR 2-6): p 
Original languageEnglish
Pages (from-to)782-789
JournalJournal of neurology
Volume266
Issue number3
DOIs
Publication statusPublished - 1 Mar 2019
Externally publishedYes

Fingerprint

Cohort Studies
Stroke
Hospital Mortality
Neuroimaging
Teaching Hospitals
Netherlands
Registries
Mortality

Keywords

  • UT-Hybrid-D
  • Off-hour effect
  • Off-hours
  • Severity
  • Stroke
  • In-hospital mortality

Cite this

Tuinman, M. P., van Golde, E. G. A., Portier, R. P., Knottnerus, I. L. H., van der Palen, J., den Hertog, H. M., & Brouwers, P. J. A. M. (2019). Comparison of outcome in stroke patients admitted during working hours vs. off-hours; a single-center cohort study. Journal of neurology, 266(3), 782-789. https://doi.org/10.1007/s00415-018-9079-1
Tuinman, M. P. ; van Golde, E. G.A. ; Portier, R. P. ; Knottnerus, I. L.H. ; van der Palen, J. ; den Hertog, H. M. ; Brouwers, P. J.A.M. / Comparison of outcome in stroke patients admitted during working hours vs. off-hours; a single-center cohort study. In: Journal of neurology. 2019 ; Vol. 266, No. 3. pp. 782-789.
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Tuinman, MP, van Golde, EGA, Portier, RP, Knottnerus, ILH, van der Palen, J, den Hertog, HM & Brouwers, PJAM 2019, 'Comparison of outcome in stroke patients admitted during working hours vs. off-hours; a single-center cohort study' Journal of neurology, vol. 266, no. 3, pp. 782-789. https://doi.org/10.1007/s00415-018-9079-1

Comparison of outcome in stroke patients admitted during working hours vs. off-hours; a single-center cohort study. / Tuinman, M. P. (Corresponding Author); van Golde, E. G.A.; Portier, R. P.; Knottnerus, I. L.H.; van der Palen, J.; den Hertog, H. M.; Brouwers, P. J.A.M.

In: Journal of neurology, Vol. 266, No. 3, 01.03.2019, p. 782-789.

Research output: Contribution to journalArticleAcademicpeer-review

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AB - INTRODUCTION We aimed to disprove an in-hospital off-hour effect in stroke patients by adjusting for disease severity and poor prognostic findings on imaging. PATIENTS AND METHODS Our study included 5378 patients from a single center prospective stroke registry of a large teaching hospital in the Netherlands, admitted between January 2003 and June 2015. Patients were categorized by admission time, off-hours (OH) or working hours (WH). The in-hospital mortality, 7-day mortality, unfavorable functional outcome (modified Rankin scale > 2) and discharge to home were analyzed. Results were adjusted for age, sex, stroke severity (NIHSS score) and unfavorable findings on imaging of the brain (midline shift and dense vessel sign). RESULTS Overall, 2796 patients (52%) were admitted during OH, which had a higher NIHSS score [3 (IQR 2-8) vs. 3 (IQR 2-6): p 

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