Composition for treatment of inflammatory disorders

J.M. Metselaar; M.H.M. Wauben; Gerrit Storm

Composition for treatment of inflammatory disorders

J.M. Metselaar (Inventor)
, M.H.M. Wauben (Inventor)
, Gerrit Storm (Inventor)

Biomaterials Science and Technology

Research output: Patent

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Abstract

A pharmaceutical composition for parenteral administration, comprising liposomes composed of non-charged vesicle-forming lipids, including up to 20 mole percent of an amphipathic vesicle-forming lipid derivatized with polyethyleneglycol, and optionally including not more than 10 mole percent of negatively charged vesicle-forming lipids, the liposomes having a selected mean particle diameter in the size range between about 40-200 nm and containing a water soluble corticosteroid for the site-specific treatment of inflammatory disorders, is provided.

Original language	English
Patent number	US2004037875
IPC	A61P 29/ 00 A I
Priority date	7/12/01
Publication status	Published - 26 Feb 2004

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abstract = "A pharmaceutical composition for parenteral administration, comprising liposomes composed of non-charged vesicle-forming lipids, including up to 20 mole percent of an amphipathic vesicle-forming lipid derivatized with polyethyleneglycol, and optionally including not more than 10 mole percent of negatively charged vesicle-forming lipids, the liposomes having a selected mean particle diameter in the size range between about 40-200 nm and containing a water soluble corticosteroid for the site-specific treatment of inflammatory disorders, is provided.",

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AU - Storm, Gerrit

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AB - A pharmaceutical composition for parenteral administration, comprising liposomes composed of non-charged vesicle-forming lipids, including up to 20 mole percent of an amphipathic vesicle-forming lipid derivatized with polyethyleneglycol, and optionally including not more than 10 mole percent of negatively charged vesicle-forming lipids, the liposomes having a selected mean particle diameter in the size range between about 40-200 nm and containing a water soluble corticosteroid for the site-specific treatment of inflammatory disorders, is provided.

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Composition for treatment of inflammatory disorders

Abstract

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