Abstract
Ultrasound contrast agents oscillate approximately linearly up to a certain pressure range where nonlinearity sets in. Nonlinear microbubble oscillations are exploited in ultrasound pulse-echo imaging as this improves the contrast-to-tissue ratio. Here we report the observation of a highly nonlinear response of phospholipid-coated contrast agents at pressures as low as 50 kPa, termed “compression-only” behavior, where the microbubbles only compress, yet hardly expand. Time-resolved bubble dynamics recorded through ultra high-speed imaging revealed that nearly 40% of the coated bubbles show “compression-only” behavior
Original language | Undefined |
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Pages (from-to) | 653-656 |
Number of pages | 4 |
Journal | Ultrasound in medicine and biology |
Volume | 33 |
Issue number | 4 |
DOIs | |
Publication status | Published - 2007 |
Keywords
- IR-74893
- METIS-239089