Computation of blood flow through collateral circulation of the superficial femoral artery

R.R. Kruse, E.J. Vinke, F.B. Poelmann, D. Rohof, S. Holewijn, C.H. Slump, M.M.P.J. Reijnen*

*Corresponding author for this work

    Research output: Contribution to journalArticleAcademicpeer-review

    4 Citations (Scopus)

    Abstract

    Objective: Obliteration of collaterals during (endo)vascular treatment of peripheral arterial occlusive disease is considered detrimental. We use a model to calculate maximum collateral bed flow of the superficial femoral artery in order to provide insight in their hemodynamic relevance.

    Method: A computational model was developed using digital subtraction angiographies in combination with Poiseuille's equation and Ohm's law. Lesions were divided into short and long (15 cm and ≥15 cm, respectively) and into stenosis and occlusions. Data are presented in relation to the calculated maximum healthy superficial femoral artery flow.

    Results: Stenotic lesions are longer than occlusive lesions (P 0.05) and occlusions had more and larger collaterals (P 0.05). In all four study groups the collateral flow significantly increased the total flow (P 0.05). The maximum collateral system flow in the stenosis and occlusion groups was 5.1% and 20.8% of healthy superficial femoral artery flow, respectively (P 0.05), and there were no significant differences between short and long lesions (11.2% and 6.7% of healthy superficial femoral artery flow, respectively).

    Conclusion: The maximum collateral system flow of the superficial femoral artery is only a fraction, with a maximum of one fifth, of healthy superficial femoral artery flow. Effects of collateral vessel occlusion during (endo)vascular treatment may therefore be without detrimental consequences.

    Original languageEnglish
    Pages (from-to)126-133
    Number of pages8
    JournalVascular
    Volume24
    Issue number2
    DOIs
    Publication statusPublished - 1 Apr 2016

    Keywords

    • Collaterals
    • Computational model
    • Covered stent
    • Flow
    • Superficial femoral artery

    Fingerprint Dive into the research topics of 'Computation of blood flow through collateral circulation of the superficial femoral artery'. Together they form a unique fingerprint.

    Cite this