Computer Aided Diagnosis for mental health care: On the Clinical Validation of Sensitive Machines

Frans van der Sluis, Ton Dijkstra, Egon van den Broek

    Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

    2 Citations (Scopus)
    31 Downloads (Pure)


    This study explores the feasibility of sensitive machines; that is, machines with empathic abilities, at least to some extent. A signal processing and machine learning pipeline is presented that is used to analyze data from two studies in which 25 Post-Traumatic Stress Disorder (PTSD) patients participated. The feasibility of speech as a stress detector was validated in a clinical setting, using the Subjective Unit of Distress (SUD). 13 statistical parameters were derived from five speech features, namely: amplitude, zero crossings, power, high-frequency power, and pitch. To achieve a low dimensional representation, a subset of 28 parameters was selected and, subsequently, compressed into 11 principal components (PC). Using a Multi-Layer Perceptron neural network (MLP), the set of 11 PC were mapped upon 9 distinct quantizations of the SUD. The MLP was able to discriminate between 2 stress levels with 82.4% accuracy and up to 10 stress levels with 36.3% accuracy. With stress baptized as being the black death of the 21st century, this work can be conceived as an important step towards computer aided mental health care.
    Original languageUndefined
    Title of host publicationProceedings of the International Conference on Health Informatics, HealthInf 2012
    EditorsE. Conchon, C. Correia, A. Fred, H. Gamboa
    Place of PublicationPortugal
    Number of pages7
    ISBN (Print)978-989-8425-88-1
    Publication statusPublished - 1 Feb 2012
    EventInternational Conference on Health Informatics, HEALTHINF 2012 - Vilamoura, Algarve, Portugal
    Duration: 1 Feb 20124 Feb 2012

    Publication series

    PublisherSciTePress - Science and Technology Publications


    ConferenceInternational Conference on Health Informatics, HEALTHINF 2012
    Other1-4 February 2012


    • METIS-285126
    • IR-79668
    • Stress
    • Speech
    • Validation
    • HMI-HF: Human Factors
    • Mental healthcare
    • Computer Aided Diagnostics (CAD)
    • EWI-21504
    • HMI-SLT: Speech and Language Technology
    • artificial neural network

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