Computer simulation of oculomotor control in extrapyramidal disorders

L. J. Bour*, A. Wolzak, D. Van't Ent, J. D. Speelman, B. W. Ongerboer de Visser

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

1 Citation (Scopus)
13 Downloads (Pure)

Abstract

Computer simulation with a model of the saccadic burst generator, proposed by C. A. Scudder (1988), demonstrated that metrics of saccades as well as their velocity characteristics can be altered without changing the characteristics of the burst generator itself. The model could be used to explain impairment of saccadic eye movements in, for instance, Parkinson's disease (PD), since in this disorder at brainstem level pontine structures, where the burst generator is located, are unaffected. Comparison of saccades in PD patients with computer simulations showed that the model provided reasonable explanation for the observed reduction in maximum saccade velocity, but is not appropriate to explain hypometria of saccades.

Original languageEnglish
Title of host publicationProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society 1991
Place of PublicationPiscataway, NJ
PublisherIEEE
Pages2307-2308
Number of pages2
Volume5
ISBN (Print)0-7803-0216-8, 0-7803-0217-6
DOIs
Publication statusPublished - 1 Dec 1991
Event13th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 1991 - Orlando, United States
Duration: 31 Oct 19913 Nov 1991
Conference number: 13

Publication series

NameProceedings of the Annual Conference on Engineering in Medicine and Biology
PublisherIEEE
Volume13
ISSN (Print)0589-1019

Conference

Conference13th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 1991
Abbreviated titleEMBC
CountryUnited States
CityOrlando
Period31/10/913/11/91

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