Concentration polarization in nanochannel DNA electrophoresis

P. Dubsky, Siddhartha Das, Albert van den Berg, Jan C.T. Eijkel

    Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

    1 Downloads (Pure)

    Abstract

    We demonstrate that the large field electrophoresis of a single DNA molecule in nanofluidic systems is accompanied by concentration polarization. We illustrate this phenomena by utilizing our electrophoretic simulation tool SIMUL. First we in-vestigate a simple system with univalent strong electrolyte as a bulk solution. Second, a more complicated system with buf-fering background electrolyte is examined. Concentration polarization in the vicinity of the DNA is observed in both the sys-tems. The practical impact of such observations are also discussed.
    Original languageUndefined
    Title of host publication15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, μTAS 2011
    Place of PublicationWashington
    PublisherChemical and Biological Micro Systems Society
    Pages212-214
    Number of pages3
    ISBN (Print)978-0-979-8064-4-5
    Publication statusPublished - 2 Oct 2011
    Event15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2011 - Seattle, United States
    Duration: 2 Oct 20116 Oct 2011
    Conference number: 15
    https://microtasconferences.org/microtas2011/

    Publication series

    Name
    PublisherChemical and Biological Microsystems Society
    ISSN (Print)1556-5904

    Conference

    Conference15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2011
    Abbreviated titleMicroTAS
    CountryUnited States
    CitySeattle
    Period2/10/116/10/11
    Internet address

    Keywords

    • METIS-281589
    • Nanochannel
    • DNA
    • EWI-20882
    • IR-78650
    • Electrophoresis
    • Concentration polarization

    Cite this