In many separation processes e.g. electrophoresis, chromatography, and membrane ultrafiltration, polymers being separated are able to deform in order to enter a narrow pore. This has implications for, for example, molecular weight cut off (MWCO) experiments where typically linear polymers like polydextran of PEG are used to measure the pore sizes of ultrafiltration membranes. The study reported in this thesis has, therefore, concentrated on the deformation of linear polymers at their entry into a pore. Pore entry was studied by means of Monte Carlo Bias simulations. Linear, flexible chains measuring 50 repeat units were used to obtain energetic and conformation related properties of partially penetrated polymers. Their values were compared to their unconfined and completely confined values.
|Award date||5 Sep 2003|
|Place of Publication||Enschede|
|Publication status||Published - 5 Sep 2003|