Continuous Flow Versus Stopped flow in A Micro flow Injection System

E.B. van Akker; M. Bos; A. van den Berg; W.E. van der Linden

doi:10.1007/978-94-011-5286-0_78

Continuous Flow Versus Stopped flow in A Micro flow Injection System

E.B. van Akker, M. Bos, A. van den Berg, W.E. van der Linden

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Abstract

The effects of continuous, pulsed and stopped flow on the dispersion of a dye in a micro flow injection system were studied experimentally and by digital simulation. A channel of 200 μm by 200 μm by 21550 μm was used to compare experimental results with the numerical results. Furthermore the injection of the dye into the flow system was studied. Video recordings of the injection were compared to simulations during and just after the injection.

Different flow rates ranging from 0.5 to 5.0 μl/min were used to study the continuous flow. The time where the flow was stopped to study the effect on the dispersion ranged from 10 to 400 seconds. The pulse frequency, to study the pulsed flow, ranged from 6 Hz to 0.1 Hz.

The numerical model used in this paper shows an excellent agreement with the experimental values obtained. The video recordings compared to numerical simulations show that the numerical model could be used to model the injection.

The general numerical model allows the calculating of the flow profile, pressure distribution and the concentration distribution of the sample, three dimensional, throughout an arbitrary channel.

Original language	English
Title of host publication	Micro Total analysis Systems '98
Subtitle of host publication	Proceedings of the uTAS ’98 Workshop, held in Banff, Canada, 13–16 October 1998
Editors	D. Jed Harrison, Albert van den Berg
Place of Publication	Dordrecht
Publisher	Kluwer Academic Publishers
Pages	335-338
ISBN (Electronic)	978-94-011-5286-0
ISBN (Print)	978-94-010-6225-1
DOIs	https://doi.org/10.1007/978-94-011-5286-0_78
Publication status	Published - 13 Oct 1998
Event	3rd International Workshop on Micro Total Analysis Systems, μTAS 1998 - Banff, Canada Duration: 13 Oct 1998 → 16 Oct 1998 Conference number: 3

Workshop

Workshop	3rd International Workshop on Micro Total Analysis Systems, μTAS 1998
Abbreviated title	MicroTAS
Country/Territory	Canada
City	Banff
Period	13/10/98 → 16/10/98

Keywords

Flow-injection
Numerical modeling

Access to Document

10.1007/978-94-011-5286-0_78

Cite this

van Akker, E. B., Bos, M., van den Berg, A., & van der Linden, W. E. (1998). Continuous Flow Versus Stopped flow in A Micro flow Injection System. In D. J. Harrison, & A. van den Berg (Eds.), Micro Total analysis Systems '98: Proceedings of the uTAS ’98 Workshop, held in Banff, Canada, 13–16 October 1998 (pp. 335-338). Kluwer Academic Publishers. https://doi.org/10.1007/978-94-011-5286-0_78

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abstract = "The effects of continuous, pulsed and stopped flow on the dispersion of a dye in a micro flow injection system were studied experimentally and by digital simulation. A channel of 200 μm by 200 μm by 21550 μm was used to compare experimental results with the numerical results. Furthermore the injection of the dye into the flow system was studied. Video recordings of the injection were compared to simulations during and just after the injection.Different flow rates ranging from 0.5 to 5.0 μl/min were used to study the continuous flow. The time where the flow was stopped to study the effect on the dispersion ranged from 10 to 400 seconds. The pulse frequency, to study the pulsed flow, ranged from 6 Hz to 0.1 Hz.The numerical model used in this paper shows an excellent agreement with the experimental values obtained. The video recordings compared to numerical simulations show that the numerical model could be used to model the injection.The general numerical model allows the calculating of the flow profile, pressure distribution and the concentration distribution of the sample, three dimensional, throughout an arbitrary channel.",

keywords = "Flow-injection, Numerical modeling",

author = "{van Akker}, E.B. and M. Bos and {van den Berg}, A. and {van der Linden}, W.E.",

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van Akker, EB, Bos, M, van den Berg, A & van der Linden, WE 1998, Continuous Flow Versus Stopped flow in A Micro flow Injection System. in DJ Harrison & A van den Berg (eds), Micro Total analysis Systems '98: Proceedings of the uTAS ’98 Workshop, held in Banff, Canada, 13–16 October 1998. Kluwer Academic Publishers, Dordrecht, pp. 335-338, 3rd International Workshop on Micro Total Analysis Systems, μTAS 1998, Banff, Canada, 13/10/98. https://doi.org/10.1007/978-94-011-5286-0_78

Continuous Flow Versus Stopped flow in A Micro flow Injection System. / van Akker, E.B.; Bos, M.; van den Berg, A. et al.
Micro Total analysis Systems '98: Proceedings of the uTAS ’98 Workshop, held in Banff, Canada, 13–16 October 1998. ed. / D. Jed Harrison; Albert van den Berg. Dordrecht: Kluwer Academic Publishers, 1998. p. 335-338.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

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AU - Bos, M.

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AU - van der Linden, W.E.

N1 - Conference code: 3

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N2 - The effects of continuous, pulsed and stopped flow on the dispersion of a dye in a micro flow injection system were studied experimentally and by digital simulation. A channel of 200 μm by 200 μm by 21550 μm was used to compare experimental results with the numerical results. Furthermore the injection of the dye into the flow system was studied. Video recordings of the injection were compared to simulations during and just after the injection.Different flow rates ranging from 0.5 to 5.0 μl/min were used to study the continuous flow. The time where the flow was stopped to study the effect on the dispersion ranged from 10 to 400 seconds. The pulse frequency, to study the pulsed flow, ranged from 6 Hz to 0.1 Hz.The numerical model used in this paper shows an excellent agreement with the experimental values obtained. The video recordings compared to numerical simulations show that the numerical model could be used to model the injection.The general numerical model allows the calculating of the flow profile, pressure distribution and the concentration distribution of the sample, three dimensional, throughout an arbitrary channel.

AB - The effects of continuous, pulsed and stopped flow on the dispersion of a dye in a micro flow injection system were studied experimentally and by digital simulation. A channel of 200 μm by 200 μm by 21550 μm was used to compare experimental results with the numerical results. Furthermore the injection of the dye into the flow system was studied. Video recordings of the injection were compared to simulations during and just after the injection.Different flow rates ranging from 0.5 to 5.0 μl/min were used to study the continuous flow. The time where the flow was stopped to study the effect on the dispersion ranged from 10 to 400 seconds. The pulse frequency, to study the pulsed flow, ranged from 6 Hz to 0.1 Hz.The numerical model used in this paper shows an excellent agreement with the experimental values obtained. The video recordings compared to numerical simulations show that the numerical model could be used to model the injection.The general numerical model allows the calculating of the flow profile, pressure distribution and the concentration distribution of the sample, three dimensional, throughout an arbitrary channel.

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KW - Numerical modeling

U2 - 10.1007/978-94-011-5286-0_78

DO - 10.1007/978-94-011-5286-0_78

M3 - Conference contribution

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EP - 338

BT - Micro Total analysis Systems '98

A2 - Harrison, D. Jed

A2 - van den Berg, Albert

PB - Kluwer Academic Publishers

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T2 - 3rd International Workshop on Micro Total Analysis Systems, μTAS 1998

Y2 - 13 October 1998 through 16 October 1998

ER -

van Akker EB, Bos M, van den Berg A, van der Linden WE. Continuous Flow Versus Stopped flow in A Micro flow Injection System. In Harrison DJ, van den Berg A, editors, Micro Total analysis Systems '98: Proceedings of the uTAS ’98 Workshop, held in Banff, Canada, 13–16 October 1998. Dordrecht: Kluwer Academic Publishers. 1998. p. 335-338 doi: 10.1007/978-94-011-5286-0_78