Continuous-wave laser generated jets for needle free applications

Carla Berrospe-Rodriguez; C.W. Visser; Stefan Schlautmann; Ruben Ramos-Garcia; David Fernandez Rivas

doi:10.1063/1.4940038

Continuous-wave laser generated jets for needle free applications

Carla Berrospe-Rodriguez, C.W. Visser, Stefan Schlautmann, Ruben Ramos-Garcia, David Fernandez Rivas

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

We designed and built a microfluidic device for the generation of liquid jets produced by thermocavitation. A continuous wave (CW) laser was focused inside a micro-chamber filled with a light-absorbing solution to create a rapidly expanding vapor bubble. The chamber is connected to a micro-channel which focuses and ejects the liquid jet through the exit. The bubble growth and the jet velocity were measured as a function of the devices geometry (channel diameter D and chamber width A). The fastest jets were those for relatively large chamber size with respect to the channel diameter. Elongated and focused jets up to 29 m/s for a channel diameter of 250 μm and chamber size of 700 μm were obtained. The proposed CW laser-based device is potentially a compact option for a practical and commercially feasible needle-free injector

Original language	English
Article number	014104
Pages (from-to)	-
Number of pages	9
Journal	Biomicrofluidics
Volume	10
Issue number	1
Early online date	13 Jan 2016
DOIs	https://doi.org/10.1063/1.4940038
Publication status	Published - Jan 2016

Keywords

METIS-315444
IR-99197

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10.1063/1.4940038

Articulopublicado1Final published version, 1.5 MBLicence: Taverne

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title = "Continuous-wave laser generated jets for needle free applications",

abstract = "We designed and built a microfluidic device for the generation of liquid jets produced by thermocavitation. A continuous wave (CW) laser was focused inside a micro-chamber filled with a light-absorbing solution to create a rapidly expanding vapor bubble. The chamber is connected to a micro-channel which focuses and ejects the liquid jet through the exit. The bubble growth and the jet velocity were measured as a function of the devices geometry (channel diameter D and chamber width A). The fastest jets were those for relatively large chamber size with respect to the channel diameter. Elongated and focused jets up to 29 m/s for a channel diameter of 250 μm and chamber size of 700 μm were obtained. The proposed CW laser-based device is potentially a compact option for a practical and commercially feasible needle-free injector",

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author = "Carla Berrospe-Rodriguez and C.W. Visser and Stefan Schlautmann and Ruben Ramos-Garcia and {Fernandez Rivas}, David",

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T1 - Continuous-wave laser generated jets for needle free applications

AU - Berrospe-Rodriguez, Carla

AU - Visser, C.W.

AU - Schlautmann, Stefan

AU - Ramos-Garcia, Ruben

AU - Fernandez Rivas, David

PY - 2016/1

Y1 - 2016/1

N2 - We designed and built a microfluidic device for the generation of liquid jets produced by thermocavitation. A continuous wave (CW) laser was focused inside a micro-chamber filled with a light-absorbing solution to create a rapidly expanding vapor bubble. The chamber is connected to a micro-channel which focuses and ejects the liquid jet through the exit. The bubble growth and the jet velocity were measured as a function of the devices geometry (channel diameter D and chamber width A). The fastest jets were those for relatively large chamber size with respect to the channel diameter. Elongated and focused jets up to 29 m/s for a channel diameter of 250 μm and chamber size of 700 μm were obtained. The proposed CW laser-based device is potentially a compact option for a practical and commercially feasible needle-free injector

AB - We designed and built a microfluidic device for the generation of liquid jets produced by thermocavitation. A continuous wave (CW) laser was focused inside a micro-chamber filled with a light-absorbing solution to create a rapidly expanding vapor bubble. The chamber is connected to a micro-channel which focuses and ejects the liquid jet through the exit. The bubble growth and the jet velocity were measured as a function of the devices geometry (channel diameter D and chamber width A). The fastest jets were those for relatively large chamber size with respect to the channel diameter. Elongated and focused jets up to 29 m/s for a channel diameter of 250 μm and chamber size of 700 μm were obtained. The proposed CW laser-based device is potentially a compact option for a practical and commercially feasible needle-free injector

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SP - -

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JF - Biomicrofluidics

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Continuous-wave laser generated jets for needle free applications

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Keywords

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