Controlling the assembly of protein cages towards functional supramolecular materials

Shuqin Cao

Research output: ThesisPhD Thesis - Research UT, graduation UT

232 Downloads (Pure)


The focus of the research reported in this thesis is to design and synthesize materials based on the protein of the Cowpea Chlorotic Mottle Virus, with the aim to control the assembly behavior by combining aspects from polymer and supramolecular chemistry. Furthermore, we studied the encasement of functional materials (gold-nanorods, carbon nanotubes and nano-diamonds) with these proteins in order to modify their properties, in particular the biocompatibility. Finally, the 3D arrangement of protein cages by non-covalent interactions is investigated. Overall, the study presented in this thesis highlights the enormous possibilities of using supramolecular interactions to obtain different dimensional biomaterials for various applications, and more knowledge on the structure and interactions between each capsid protein was obtained.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • University of Twente
  • Cornelissen, Jeroen, Supervisor
Thesis sponsors
Award date28 Feb 2020
Place of PublicationEnschede
Print ISBNs978-90-365-4954-7
Electronic ISBNs978-90-365-4954-7
Publication statusPublished - 28 Feb 2020

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