Coronary Wallstents show significant late, postprocedural expansion despite implantation with adjunct high-pressure balloon inflations

Clemens von Birgelen, Segei G. Airiian, Pim J. de Feyter, David P. Foley, Wim J. van der Giessen, Patrick W. Serruys* (Corresponding Author)

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

28 Citations (Scopus)

Abstract

Adjunct high-pressure balloon inflations following the delivery of oversized self-expandable Wallstents may affect their implied late, postprocedural self-expansion. Consequently, we examined 15 'Magic' Wallstents, which were implanted following a strategy of stent oversizing and subsequent adjunct high-pressure balloon inflations (16 ± 2 atm; all ≤ 12 atm). The excellent radiographic visibility of this stent permitted reliable quantitative coronary angiographic measurement of both lumen and stent dimensions (before and after stenting, and at follow-up). At follow-up, extent and distribution of in-stent neointimal proliferation were evaluated with volumetric intravascular ultrasound. Between postintervention and follow-up examination, mean stent diameter increased from 3.7 ± 0.4 to 4.2 ± 0.4 mm (p <0.0001); there was no significant difference in late stent expansion between proximal, mid-, and distal stent subsegments. Late stent expansion showed a significant (reverse) relation to maximum balloon size (r =-0.56, p <0.04), but not with follow-up lumen size or late lumen loss. On average, 52 ± 18% of the stent was filled with neointimal ingrowth; neointimal volume/cm stent length was 64 ± 22 mm3. Both late stent expansion (r = 0.36, p <0.02) and maximum balloon pressure (r = 0.41, p <0.001) were related to neointimal volume/cm stent but not to follow-up lumen size. Thus, despite high-pressure implantation, Wallstents showed significant late self-expansion, which resulted in larger stent dimensions at follow-up that assisted in accommodating in-stent neointimal proliferation. Conversely, late stent expansion had a significant relation to the extent of in-stent neointimal ingrowth. Beneficial and disadvantageous effects of the late stent expansion appear to be balanced, because a relation to late lumen loss or follow-up lumen dimensions was not found to be present.

Original languageEnglish
Pages (from-to)129-134
Number of pages6
JournalAmerican journal of cardiology
Volume82
Issue number2
DOIs
Publication statusPublished - 15 Jul 1998
Externally publishedYes

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