(Cost-)effectiveness of an internet-based physical activity support program (with and without physiotherapy counselling) on physical activity levels of breast and prostate cancer survivors: Design of the PABLO trial 11 Medical and Health Sciences 1117 Public Health and Health Services

H. J. Van De Wiel, M. M. Stuiver, A. M. May, S. Van Grinsven, N. K. Aaronson, V. P. Retèl, H. S.A. Oldenburg, H. G. Van Der Poel, S. Horenblas, W. H. Van Harten*, W. G. Groen

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)
14 Downloads (Pure)

Abstract

Background: Higher levels of physical activity (PA) after treatment are associated with beneficial effects on physical and psychosocial functioning of cancer survivors. However, survivors often do not meet the recommended levels of PA. In order to promote PA, we developed a closed internet-based program. The aim of the study is to evaluate the (cost-)effectiveness of an internet-based PA-promotion program, alone or combined with physiotherapy counselling, compared to usual care, on PA-levels of breast or prostate cancer survivors. In this multicenter randomised controlled trial (RCT), breast or prostate cancer survivors who completed their primary treatment 3-12 months earlier, will be randomised to either 6-months access to a fully-automated internet-based intervention alone, an internet-based intervention plus remote support by a physiotherapist, or a control group. The intervention is based on the Transtheoretical Model and includes personalized feedback, information, video's and assignments. Additionally, in a second arm, physiotherapy counselling is provided through monthly scheduled and on-demand telephone calls. The control group will receive usual care and a leaflet with PA guidelines. Methods: At baseline, 6 and 12 months, the primary outcome (PA) will be measured during 7 consecutive days by accelerometers. Secondary outcomes are self-reported PA, fatigue, mood, health-related quality of life, and costs. The group differences for primary and secondary outcomes will be analyzed using linear mixed models. Discussion: If proven to be (cost)effective, this internet-based intervention, either alone or in combination with telephone support, will be a welcome addition to previous RCT's. Trial registration: Netherlands trial register (NTR6911), Date of trial registration: December 21, 2017.

Original languageEnglish
Article number1073
JournalBMC cancer
Volume18
Issue number1
DOIs
Publication statusPublished - 6 Nov 2018

Fingerprint

Internet
Health Services
Cost-Benefit Analysis
Survivors
Counseling
Prostatic Neoplasms
Public Health
Exercise
Breast Neoplasms
Health
Telephone
Costs and Cost Analysis
Control Groups
Physical Therapists
Netherlands
Fatigue
Linear Models
Randomized Controlled Trials
Quality of Life
Guidelines

Keywords

  • Breast cancer survivors
  • Internet-based intervention
  • Physical activity
  • Prostate cancer survivors
  • RCT

Cite this

@article{1d279015331f48a4b41a72e842a9b756,
title = "(Cost-)effectiveness of an internet-based physical activity support program (with and without physiotherapy counselling) on physical activity levels of breast and prostate cancer survivors: Design of the PABLO trial 11 Medical and Health Sciences 1117 Public Health and Health Services",
abstract = "Background: Higher levels of physical activity (PA) after treatment are associated with beneficial effects on physical and psychosocial functioning of cancer survivors. However, survivors often do not meet the recommended levels of PA. In order to promote PA, we developed a closed internet-based program. The aim of the study is to evaluate the (cost-)effectiveness of an internet-based PA-promotion program, alone or combined with physiotherapy counselling, compared to usual care, on PA-levels of breast or prostate cancer survivors. In this multicenter randomised controlled trial (RCT), breast or prostate cancer survivors who completed their primary treatment 3-12 months earlier, will be randomised to either 6-months access to a fully-automated internet-based intervention alone, an internet-based intervention plus remote support by a physiotherapist, or a control group. The intervention is based on the Transtheoretical Model and includes personalized feedback, information, video's and assignments. Additionally, in a second arm, physiotherapy counselling is provided through monthly scheduled and on-demand telephone calls. The control group will receive usual care and a leaflet with PA guidelines. Methods: At baseline, 6 and 12 months, the primary outcome (PA) will be measured during 7 consecutive days by accelerometers. Secondary outcomes are self-reported PA, fatigue, mood, health-related quality of life, and costs. The group differences for primary and secondary outcomes will be analyzed using linear mixed models. Discussion: If proven to be (cost)effective, this internet-based intervention, either alone or in combination with telephone support, will be a welcome addition to previous RCT's. Trial registration: Netherlands trial register (NTR6911), Date of trial registration: December 21, 2017.",
keywords = "Breast cancer survivors, Internet-based intervention, Physical activity, Prostate cancer survivors, RCT",
author = "{Van De Wiel}, {H. J.} and Stuiver, {M. M.} and May, {A. M.} and {Van Grinsven}, S. and Aaronson, {N. K.} and Ret{\`e}l, {V. P.} and Oldenburg, {H. S.A.} and {Van Der Poel}, {H. G.} and S. Horenblas and {Van Harten}, {W. H.} and Groen, {W. G.}",
year = "2018",
month = "11",
day = "6",
doi = "10.1186/s12885-018-4927-z",
language = "English",
volume = "18",
journal = "BMC cancer",
issn = "1471-2407",
publisher = "BioMed Central Ltd.",
number = "1",

}

(Cost-)effectiveness of an internet-based physical activity support program (with and without physiotherapy counselling) on physical activity levels of breast and prostate cancer survivors : Design of the PABLO trial 11 Medical and Health Sciences 1117 Public Health and Health Services. / Van De Wiel, H. J.; Stuiver, M. M.; May, A. M.; Van Grinsven, S.; Aaronson, N. K.; Retèl, V. P.; Oldenburg, H. S.A.; Van Der Poel, H. G.; Horenblas, S.; Van Harten, W. H.; Groen, W. G.

In: BMC cancer, Vol. 18, No. 1, 1073, 06.11.2018.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - (Cost-)effectiveness of an internet-based physical activity support program (with and without physiotherapy counselling) on physical activity levels of breast and prostate cancer survivors

T2 - Design of the PABLO trial 11 Medical and Health Sciences 1117 Public Health and Health Services

AU - Van De Wiel, H. J.

AU - Stuiver, M. M.

AU - May, A. M.

AU - Van Grinsven, S.

AU - Aaronson, N. K.

AU - Retèl, V. P.

AU - Oldenburg, H. S.A.

AU - Van Der Poel, H. G.

AU - Horenblas, S.

AU - Van Harten, W. H.

AU - Groen, W. G.

PY - 2018/11/6

Y1 - 2018/11/6

N2 - Background: Higher levels of physical activity (PA) after treatment are associated with beneficial effects on physical and psychosocial functioning of cancer survivors. However, survivors often do not meet the recommended levels of PA. In order to promote PA, we developed a closed internet-based program. The aim of the study is to evaluate the (cost-)effectiveness of an internet-based PA-promotion program, alone or combined with physiotherapy counselling, compared to usual care, on PA-levels of breast or prostate cancer survivors. In this multicenter randomised controlled trial (RCT), breast or prostate cancer survivors who completed their primary treatment 3-12 months earlier, will be randomised to either 6-months access to a fully-automated internet-based intervention alone, an internet-based intervention plus remote support by a physiotherapist, or a control group. The intervention is based on the Transtheoretical Model and includes personalized feedback, information, video's and assignments. Additionally, in a second arm, physiotherapy counselling is provided through monthly scheduled and on-demand telephone calls. The control group will receive usual care and a leaflet with PA guidelines. Methods: At baseline, 6 and 12 months, the primary outcome (PA) will be measured during 7 consecutive days by accelerometers. Secondary outcomes are self-reported PA, fatigue, mood, health-related quality of life, and costs. The group differences for primary and secondary outcomes will be analyzed using linear mixed models. Discussion: If proven to be (cost)effective, this internet-based intervention, either alone or in combination with telephone support, will be a welcome addition to previous RCT's. Trial registration: Netherlands trial register (NTR6911), Date of trial registration: December 21, 2017.

AB - Background: Higher levels of physical activity (PA) after treatment are associated with beneficial effects on physical and psychosocial functioning of cancer survivors. However, survivors often do not meet the recommended levels of PA. In order to promote PA, we developed a closed internet-based program. The aim of the study is to evaluate the (cost-)effectiveness of an internet-based PA-promotion program, alone or combined with physiotherapy counselling, compared to usual care, on PA-levels of breast or prostate cancer survivors. In this multicenter randomised controlled trial (RCT), breast or prostate cancer survivors who completed their primary treatment 3-12 months earlier, will be randomised to either 6-months access to a fully-automated internet-based intervention alone, an internet-based intervention plus remote support by a physiotherapist, or a control group. The intervention is based on the Transtheoretical Model and includes personalized feedback, information, video's and assignments. Additionally, in a second arm, physiotherapy counselling is provided through monthly scheduled and on-demand telephone calls. The control group will receive usual care and a leaflet with PA guidelines. Methods: At baseline, 6 and 12 months, the primary outcome (PA) will be measured during 7 consecutive days by accelerometers. Secondary outcomes are self-reported PA, fatigue, mood, health-related quality of life, and costs. The group differences for primary and secondary outcomes will be analyzed using linear mixed models. Discussion: If proven to be (cost)effective, this internet-based intervention, either alone or in combination with telephone support, will be a welcome addition to previous RCT's. Trial registration: Netherlands trial register (NTR6911), Date of trial registration: December 21, 2017.

KW - Breast cancer survivors

KW - Internet-based intervention

KW - Physical activity

KW - Prostate cancer survivors

KW - RCT

UR - http://www.scopus.com/inward/record.url?scp=85056093146&partnerID=8YFLogxK

U2 - 10.1186/s12885-018-4927-z

DO - 10.1186/s12885-018-4927-z

M3 - Article

C2 - 30400784

AN - SCOPUS:85056093146

VL - 18

JO - BMC cancer

JF - BMC cancer

SN - 1471-2407

IS - 1

M1 - 1073

ER -