TY - JOUR
T1 - Covalent Coupling of Nanoparticles with Low-Density Functional Ligands to Surfaces via Click Chemistry
AU - Rianasari, I.
AU - de Jong, Machiel Pieter
AU - Huskens, Jurriaan
AU - van der Wiel, Wilfred Gerard
PY - 2013/2/7
Y1 - 2013/2/7
N2 - We demonstrate the application of the 1,3-dipolar cycloaddition (“click‿ reaction) to couple gold nanoparticles (Au NPs) functionalized with low densities of functional ligands. The ligand coverage on the citrate-stabilized Au NPs was adjusted by the ligand:Au surface atom ratio, while maintaining the colloidal stability of the Au NPs in aqueous solution. A procedure was developed to determine the driving forces governing the selectivity and reactivity of citrate-stabilized and ligand-functionalized Au NPs on patterned self-assembled monolayers. We observed selective and remarkably stable chemical bonding of the Au NPs to the complimentarily functionalized substrate areas, even when estimating that only 1–2 chemical bonds are formed between the particles and the substrate.
AB - We demonstrate the application of the 1,3-dipolar cycloaddition (“click‿ reaction) to couple gold nanoparticles (Au NPs) functionalized with low densities of functional ligands. The ligand coverage on the citrate-stabilized Au NPs was adjusted by the ligand:Au surface atom ratio, while maintaining the colloidal stability of the Au NPs in aqueous solution. A procedure was developed to determine the driving forces governing the selectivity and reactivity of citrate-stabilized and ligand-functionalized Au NPs on patterned self-assembled monolayers. We observed selective and remarkably stable chemical bonding of the Au NPs to the complimentarily functionalized substrate areas, even when estimating that only 1–2 chemical bonds are formed between the particles and the substrate.
KW - EWI-24406
KW - IR-89202
KW - METIS-301584
U2 - 10.3390/ijms14023705
DO - 10.3390/ijms14023705
M3 - Article
SN - 1661-6596
VL - 14
SP - 3705
EP - 3717
JO - International journal of molecular sciences
JF - International journal of molecular sciences
IS - 2
ER -