Creeping Proteins in Microporous Structures: Polymer Brush-Assisted Fabrication of 3D Gradients for Tissue Engineering

Michel Klein Gunnewiek; Andrea Di Luca; Hermannes Z. Bollemaat; Clemens van Blitterswijk; Gyula J. Vancso; Lorenzo Moroni; Edmondo Maria Benetti

doi:10.1002/adhm.201400797

Creeping Proteins in Microporous Structures: Polymer Brush-Assisted Fabrication of 3D Gradients for Tissue Engineering

Michel Klein Gunnewiek, Andrea Di Luca, Hermannes Z. Bollemaat, Clemens van Blitterswijk, Gyula J. Vancso, Lorenzo Moroni, Edmondo Maria Benetti

Research output: Contribution to journal › Article › Academic › peer-review

37 Citations (Scopus)

Abstract

Coupling of rapid prototyping techniques and surface-confined polymerizations allows the fabrication of 3D multidirectional gradients of biomolecules within microporous scaffolds. The compositional gradients can be tailored by polymer-brush-assisted diffusion of protein solutions. This technique allows spatial control over stem cells manipulation within 3D environments

Original language	Undefined
Pages (from-to)	1169-1174
Journal	Advanced healthcare materials
Volume	4
Issue number	8
DOIs	https://doi.org/10.1002/adhm.201400797
Publication status	Published - 2015

Keywords

IR-99897
METIS-314681

Access to Document

10.1002/adhm.201400797

Cite this

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title = "Creeping Proteins in Microporous Structures: Polymer Brush-Assisted Fabrication of 3D Gradients for Tissue Engineering",

abstract = "Coupling of rapid prototyping techniques and surface-confined polymerizations allows the fabrication of 3D multidirectional gradients of biomolecules within microporous scaffolds. The compositional gradients can be tailored by polymer-brush-assisted diffusion of protein solutions. This technique allows spatial control over stem cells manipulation within 3D environments",

keywords = "IR-99897, METIS-314681",

author = "{Klein Gunnewiek}, Michel and {Di Luca}, Andrea and Bollemaat, {Hermannes Z.} and {van Blitterswijk}, Clemens and Vancso, {Gyula J.} and Lorenzo Moroni and Benetti, {Edmondo Maria}",

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language = "Undefined",

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journal = "Advanced healthcare materials",

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AU - Klein Gunnewiek, Michel

AU - Di Luca, Andrea

AU - Bollemaat, Hermannes Z.

AU - van Blitterswijk, Clemens

AU - Vancso, Gyula J.

AU - Moroni, Lorenzo

AU - Benetti, Edmondo Maria

PY - 2015

Y1 - 2015

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AB - Coupling of rapid prototyping techniques and surface-confined polymerizations allows the fabrication of 3D multidirectional gradients of biomolecules within microporous scaffolds. The compositional gradients can be tailored by polymer-brush-assisted diffusion of protein solutions. This technique allows spatial control over stem cells manipulation within 3D environments

KW - IR-99897

KW - METIS-314681

U2 - 10.1002/adhm.201400797

DO - 10.1002/adhm.201400797

M3 - Article

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SP - 1169

EP - 1174

JO - Advanced healthcare materials

JF - Advanced healthcare materials

SN - 2192-2640

IS - 8

ER -