Abstract
n forced polymer translocation, the average translocation time τ scales with respect to pore force f and polymer length N as τ∼f−1Nβ. We demonstrate that an artifact in the Metropolis Monte Carlo method resulting in breakage of the force scaling with large f may be responsible for some of the controversies between different computationally obtained results and also between computational and experimental results. Using Langevin dynamics simulations we show that the scaling exponent β⩽1+ν is not universal, but depends on f. Moreover, we show that forced translocation can be described by a relatively simple force balance argument and β to arise solely from the initial polymer configuration.
| Original language | English |
|---|---|
| Article number | 061803 |
| Pages (from-to) | 1-8 |
| Number of pages | 8 |
| Journal | Physical Review E |
| Volume | 78 |
| DOIs | |
| Publication status | Published - 29 Dec 2008 |
| Externally published | Yes |
Keywords
- Biomembrane transport
- Differential equations
- Molecular biophysics
- Monte Carlo methods
- Nonlinear dynamical systems
- Polymers
- Stochastic processes
- ITC-ISI-JOURNAL-ARTICLE
- n/a OA procedure
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