Current and Future Use of Long Axial Field-of-View Positron Emission Tomography/Computed Tomography Scanners in Clinical Oncology

Mostafa Roya*, Samaneh Mostafapour, Philipp Mohr, Laura Providência, Zekai Li, Johannes H. van Snick, Adrienne H. Brouwers, Walter Noordzij, Antoon T.M. Willemsen, Rudi A.J.O. Dierckx, Adriaan A. Lammertsma, Andor W.J.M. Glaudemans, Charalampos Tsoumpas, Riemer H.J.A. Slart*, Joyce van Sluis

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

5 Citations (Scopus)
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Abstract

The latest technical development in the field of positron emission tomography/computed tomography (PET/CT) imaging has been the extension of the PET axial field-of-view. As a result of the increased number of detectors, the long axial field-of-view (LAFOV) PET systems are not only characterized by a larger anatomical coverage but also by a substantially improved sensitivity, compared with conventional short axial field-of-view PET systems. In clinical practice, this innovation has led to the following optimization: (1) improved overall image quality, (2) decreased duration of PET examinations, (3) decreased amount of radioactivity administered to the patient, or (4) a combination of any of the above. In this review, novel applications of LAFOV PET in oncology are highlighted and future directions are discussed.

Original languageEnglish
Article number5173
Number of pages21
JournalCancers
Volume15
Issue number21
Early online date27 Oct 2023
DOIs
Publication statusPublished - Nov 2023

Keywords

  • dual-tracer imaging
  • LAFOV PET/CT
  • parametric imaging
  • protocol optimization

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