Current status of treatment for diverticulitis

Bryan Joost Marinus van de Wall

    Research output: ThesisPhD Thesis - Research external, graduation UT

    331 Downloads (Pure)

    Abstract

    Diverticula are outpouchings that occur at week points in the colonic wall where small blood vessels enter the circular muscle layer. Diverticula are most frequently found in the distal part of the colon, with 90% of patients having the sigmoid colon involved. Most patients who have diverticulosis remain asymptomatic; however an estimated 15-20% will develop diverticulitis. Acute diverticulitis is a complication of diverticulosis that occurs when these outpouchings become infected. It is theorised that inflammation occurs when the entrance to the diverticulum is obstructed by faecal matter leading to bacterial overgrowth and partial necrosis of the diverticular wall. To date, consensus appears to be lacking on several aspects regarding the diagnostic approach and treatment of diverticulitis. This has led to a joint Dutch initiative, the Dutch Diverticular Disease Collaborative Study Group. This study group is a cooperation of the Academic Medical Center Amsterdam, Erasmus Medical Center Rotterdam, Kennemer Hospital Haarlem, Meander Medical Center Amersfoort, Saint Lucas Andreas Hospital Amsterdam aiming to deliver evidence in the form of both retrospective and prospective studies to end these persisting controversies.
    Original languageEnglish
    Awarding Institution
    • University of Twente
    Supervisors/Advisors
    • Broeders, Ivo Adriaan Maria Johannes, Supervisor
    • Consten, Esther C.J., Advisor, External person
    • Draaisma, Werner A., Advisor, External person
    Thesis sponsors
    Award date11 Apr 2013
    Place of PublicationEnschede
    Publisher
    Print ISBNs978-94-6108-426-2
    Publication statusPublished - 11 Apr 2013

    Fingerprint

    Diverticulitis
    Diverticulum
    Therapeutics
    Sigmoid Colon
    Blood Vessels
    Colon
    Necrosis
    Retrospective Studies
    Joints
    Prospective Studies
    Inflammation
    Muscles

    Keywords

    • EWI-24636
    • METIS-303015
    • Diverticulitis
    • IR-90457

    Cite this

    van de Wall, B. J. M. (2013). Current status of treatment for diverticulitis. Enschede: Universiteit Twente.
    van de Wall, Bryan Joost Marinus. / Current status of treatment for diverticulitis. Enschede : Universiteit Twente, 2013. 164 p.
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    van de Wall, BJM 2013, 'Current status of treatment for diverticulitis', University of Twente, Enschede.

    Current status of treatment for diverticulitis. / van de Wall, Bryan Joost Marinus.

    Enschede : Universiteit Twente, 2013. 164 p.

    Research output: ThesisPhD Thesis - Research external, graduation UT

    TY - THES

    T1 - Current status of treatment for diverticulitis

    AU - van de Wall, Bryan Joost Marinus

    PY - 2013/4/11

    Y1 - 2013/4/11

    N2 - Diverticula are outpouchings that occur at week points in the colonic wall where small blood vessels enter the circular muscle layer. Diverticula are most frequently found in the distal part of the colon, with 90% of patients having the sigmoid colon involved. Most patients who have diverticulosis remain asymptomatic; however an estimated 15-20% will develop diverticulitis. Acute diverticulitis is a complication of diverticulosis that occurs when these outpouchings become infected. It is theorised that inflammation occurs when the entrance to the diverticulum is obstructed by faecal matter leading to bacterial overgrowth and partial necrosis of the diverticular wall. To date, consensus appears to be lacking on several aspects regarding the diagnostic approach and treatment of diverticulitis. This has led to a joint Dutch initiative, the Dutch Diverticular Disease Collaborative Study Group. This study group is a cooperation of the Academic Medical Center Amsterdam, Erasmus Medical Center Rotterdam, Kennemer Hospital Haarlem, Meander Medical Center Amersfoort, Saint Lucas Andreas Hospital Amsterdam aiming to deliver evidence in the form of both retrospective and prospective studies to end these persisting controversies.

    AB - Diverticula are outpouchings that occur at week points in the colonic wall where small blood vessels enter the circular muscle layer. Diverticula are most frequently found in the distal part of the colon, with 90% of patients having the sigmoid colon involved. Most patients who have diverticulosis remain asymptomatic; however an estimated 15-20% will develop diverticulitis. Acute diverticulitis is a complication of diverticulosis that occurs when these outpouchings become infected. It is theorised that inflammation occurs when the entrance to the diverticulum is obstructed by faecal matter leading to bacterial overgrowth and partial necrosis of the diverticular wall. To date, consensus appears to be lacking on several aspects regarding the diagnostic approach and treatment of diverticulitis. This has led to a joint Dutch initiative, the Dutch Diverticular Disease Collaborative Study Group. This study group is a cooperation of the Academic Medical Center Amsterdam, Erasmus Medical Center Rotterdam, Kennemer Hospital Haarlem, Meander Medical Center Amersfoort, Saint Lucas Andreas Hospital Amsterdam aiming to deliver evidence in the form of both retrospective and prospective studies to end these persisting controversies.

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    KW - METIS-303015

    KW - Diverticulitis

    KW - IR-90457

    M3 - PhD Thesis - Research external, graduation UT

    SN - 978-94-6108-426-2

    PB - Universiteit Twente

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    van de Wall BJM. Current status of treatment for diverticulitis. Enschede: Universiteit Twente, 2013. 164 p.