TY - JOUR
T1 - Decreased stress shielding with a PEEK femoral total knee prosthesis measured in validated computational models
AU - de Ruiter, Lennert
AU - Rankin, Kathryn
AU - Browne, Martin
AU - Briscoe, Adam
AU - Janssen, Dennis
AU - Verdonschot, Nico
N1 - Funding Information:
A.B. is a paid employee of Invibio Ltd. and had a role in the study design and review of the manuscript. M.B. has received research funding support from Invibio Ltd. N.V. is a consultant to Invibio Ltd. The other authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data.
Publisher Copyright:
© 2021 The Author(s)
PY - 2021/3/30
Y1 - 2021/3/30
N2 - Due to their high stiffness, metal femoral implants in total knee arthroplasty may cause stress shielding of the peri-prosthetic bone, which can lead to loss of bone stock. Using a polymer (PEEK) femoral implant reduces the stiffness mismatch between implant and bone, and therefore has the potential to decrease strain shielding. The goal of the current study was to evaluate this potential benefit of PEEK femoral components in cadaveric experiments. Cadaveric femurs were loaded in a materials testing device, while a 3-D digital image correlation set-up captured strains on the surface of the intact femurs and femurs implanted with PEEK and CoCr components. These experimental results were used to validate specimen-specific finite element models, which subsequently were used to assess the effect of metal and PEEK femoral components on the bone strain energy density. The finite element models showed strain maps that were highly comparable to the experimental measurements. The PEEK implant increased strain energy density, relative to the preoperative bone and compared to CoCr. This was most pronounced in the regions directly under the implant and near load contact sites. These data confirm the hypothesis that a PEEK femoral implant can reduce peri-prosthetic stress shielding.
AB - Due to their high stiffness, metal femoral implants in total knee arthroplasty may cause stress shielding of the peri-prosthetic bone, which can lead to loss of bone stock. Using a polymer (PEEK) femoral implant reduces the stiffness mismatch between implant and bone, and therefore has the potential to decrease strain shielding. The goal of the current study was to evaluate this potential benefit of PEEK femoral components in cadaveric experiments. Cadaveric femurs were loaded in a materials testing device, while a 3-D digital image correlation set-up captured strains on the surface of the intact femurs and femurs implanted with PEEK and CoCr components. These experimental results were used to validate specimen-specific finite element models, which subsequently were used to assess the effect of metal and PEEK femoral components on the bone strain energy density. The finite element models showed strain maps that were highly comparable to the experimental measurements. The PEEK implant increased strain energy density, relative to the preoperative bone and compared to CoCr. This was most pronounced in the regions directly under the implant and near load contact sites. These data confirm the hypothesis that a PEEK femoral implant can reduce peri-prosthetic stress shielding.
KW - Digital image correlation
KW - Finite element simulation
KW - Polyetheretherketone
KW - Stress shielding
KW - Total knee arthroplasty
KW - UT-Hybrid-D
UR - http://www.scopus.com/inward/record.url?scp=85100474552&partnerID=8YFLogxK
U2 - 10.1016/j.jbiomech.2021.110270
DO - 10.1016/j.jbiomech.2021.110270
M3 - Article
C2 - 33578052
SN - 0021-9290
VL - 118
JO - Journal of biomechanics
JF - Journal of biomechanics
M1 - 110270
ER -