Flood frequency curves are usually highly uncertain since they are based on short data sets of measured discharges or weather conditions. To decrease the confidence intervals, an efficient bootstrap method is developed in this study. The Rhine river delta is considered as a case study. We use a hydraulic model to normalize historic flood events for anthropogenic and natural changes in the river system. As a result, the data set of measured discharges could be extended by approximately 600 years. The study shows that historic flood events decrease the confidence interval of the flood frequency curve significantly, specifically in the range of large floods. This even applies if the maximum discharges of these historic flood events are highly uncertain themselves.