Defocus Blur Synthesis and Deblurring via Interpolation and Extrapolation in Latent Space

Ioana Mazilu, Shunxin Wang*, Sven Dummer, Raymond Veldhuis, Christoph Brune, Nicola Strisciuglio

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

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Abstract

Though modern microscopes have an autofocusing system to ensure optimal focus, out-of-focus images can still occur when cells within the medium are not all in the same focal plane, affecting the image quality for medical diagnosis and analysis of diseases. We propose a method that can deblur images as well as synthesize defocus blur. We train autoencoders with implicit and explicit regularization techniques to enforce linearity relations among the representations of different blur levels in the latent space. This allows for the exploration of different blur levels of an object by linearly interpolating/extrapolating the latent representations of images taken at different focal planes. Compared to existing works, we use a simple architecture to synthesize images with flexible blur levels, leveraging the linear latent space. Our regularized autoencoders can effectively mimic blur and deblur, increasing data variety as a data augmentation technique and improving the quality of microscopic images, which would be beneficial for further processing and analysis. The code is available at https://github.com/nis-research/linear-latent-blur.

Original languageEnglish
Title of host publicationComputer Analysis of Images and Patterns
Subtitle of host publication20th International Conference, CAIP 2023, Limassol, Cyprus, September 25–28, 2023, Proceedings
EditorsNicolas Tsapatsoulis, Efthyvoulos Kyriacou, Andreas Lanitis, Zenonas Theodosiou, Marios Pattichis, Constantinos Pattichis, Christos Kyrkou, Andreas Panayides
Place of PublicationCham
PublisherSpringer
Pages201-211
Number of pages11
ISBN (Electronic)978-3-031-44240-7
ISBN (Print)978-3-031-44239-1
DOIs
Publication statusPublished - 2023
Event20th International Conference on Computer Analysis of Images and Patterns, CAIP 2023 - Limassol, Cyprus
Duration: 25 Sept 202328 Sept 2023
Conference number: 20

Publication series

NameLecture Notes in Computer Science
PublisherSpringer
Volume14185
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference20th International Conference on Computer Analysis of Images and Patterns, CAIP 2023
Abbreviated titleCAIP 2023
Country/TerritoryCyprus
CityLimassol
Period25/09/2328/09/23

Keywords

  • Deblurring
  • Defocus blur synthesis
  • Microscope images
  • Regularized autoencoders

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